Publications by authors named "Zhenxin Jiang"

Article Synopsis
  • Arginase contributes to the development of an immunosuppressive environment in colorectal cancer, making the disease less responsive to immunotherapy; its activity in macrophages skews them toward a less effective M2-like polarization.
  • The study introduced a microparticle formulation (PG/ICG@MPs) that combines the natural compound piceatannol 3'-O-glucoside and indocyanine green to target tumors and modify immune responses through inhibiting arginase and enhancing nitric oxide levels.
  • Results showed that PG/ICG@MPs effectively promote the repolarization of macrophages towards the M1 phenotype and boost tumor immunity, demonstrating promising potential for combined cancer therapies that can be translated into clinical
View Article and Find Full Text PDF
Article Synopsis
  • Data on the blockchain is secure from tampering, but insider threats can still leak sensitive information; thus, access records are crucial for tracing breaches, though they can also be altered.
  • To safeguard these access records, the paper introduces a novel storage mechanism using a master-slave block structure in a consortium chain, where the master block holds the data and the slave block contains the access records.
  • Real-world experiments demonstrate that this new storage approach not only enhances the security and traceability of access records but also improves data query performance compared to traditional single chain methods.
View Article and Find Full Text PDF

A Kerr-lens mode-locked laser based on a Yb-doped disordered gadolinium scandate (Yb:GdScO) crystal is reported for the first time, to the best of our knowledge. The crystal with the perovskite structure was grown using the Czochralski method, and its room temperature (RT) and low temperature (LT) spectra were also investigated. Due to the crystal's multisite structure (Gd/Sc site), Yb:GdScO offers broad and intense polarized emission spectra in the near-infrared range (975-1075 nm).

View Article and Find Full Text PDF