Currently, the photodetectors (PDs) assembled by vertically aligned nanostructured arrays have attracted intensive interest owing to their unique virtues of low light reflectivity and rapid charge transport. However, in terms of the inherent limitations caused by numerous interfaces often existed within the assembled arrays, the photogenerated carriers cannot be effectively separated, thus weakening the performance of target PDs. Aiming at resolving this critical point, a high-performance ultraviolet (UV) PD with a single-crystal integrated self-supporting 4H-SiC nanohole arrays is constructed, which are prepared via the anode oxidation approach.
View Article and Find Full Text PDFThe in-situ reduction of zero-valent iron (ZVI) is an effective method for removing chlorinated aliphatic hydrocarbons (CAHs) from groundwater. The heterogeneity of environmental conditions is also crucial in affecting dechlorination efficiency. Until now, the effect of Sulfate (SO) on ZVI activity has been debated, and the related mechanism research on SO behaviour during the abiotic reduction process of chlorinated alkanes is still lacking.
View Article and Find Full Text PDFThe proportion of activated persulfate (PS) oxidation technology in the remediation of domestic organic contaminated sites has increased every year, and the potential corrosion risk of site reuse caused by residual oxidants and by-products has also attracted the attention of researchers. In this work, the potential corrosion degree such as the mass reduction rate and surface crack width of standard iron flakes under different conditions, including with different PS dosages and release times, was monitored quantitatively over a long period, and the corresponding corrosion risk was quantitatively assessed. The results showed that when n (NaSO):n (PAHs) increased from 5:1 to 100:1, the higher the oxidizer dosage, the more severe the corrosion weight loss and surface crack width, indicating that the oxidizer dosage was positively correlated with the potential corrosion risk.
View Article and Find Full Text PDFThere is little information concerning whether incorporating clinically significant portal hypertension (CSPH) into albumin-bilirubin (ALBI) grading could improve its predictive capacity. In this study, we investigated the predictive ability of ALBI grade plus CSPH (ALBI-P score) for patients with hepatocellular carcinoma (HCC) after liver resection. Data from 1,679 patients were retrospectively reviewed.
View Article and Find Full Text PDFInflammation-based markers are considered prognostic indicators for patients with hepatocellular carcinoma (HCC) after liver resection. However, there is little information concerning whether they are useful for HCC patients with clinically significant portal hypertension (CSPH). In this study, 1452 patients were enrolled.
View Article and Find Full Text PDFACS Appl Mater Interfaces
May 2020
Improving the sensitivity of the piezoresistive behavior of semiconductor nanostructures is critically important because it is one of the keys to explore advanced pressure sensors with desired sensitivity. Herein, we reported a strategy for improving the piezoresistive behavior of SiC nanowire by coupling with the piezoelectric effect of ZnO nanolayers, which were grown by an atomic layer deposition approach. As a result, the detected current of the as-constructed ZnO/SiC heterojunction nanowires is 6 times more than SiC nanowires, suggesting its substantially improved sensitivity.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2019
Rationale: Glucagonoma is a rare neuroendocrine tumor of the pancreas. Glucagonoma syndrome is often misdiagnosed as other skin lesions by clinicians due to a typical clinical sign of necrolytic migratory erythema (NME) with severe erythematous rash.
Patient Concerns: A 48-year-old female patient was admitted to our department because she presented with unclear recurrent severe erythematous rash.
Comp Immunol Microbiol Infect Dis
June 2019
Sepsis is a life-threatening condition that may develop to multiple organ failure and septic shock. Autophagy is considered to play an important role in the regulation of inflammation. The present study aims to investigate the protective role of mTORC1 inhibitor, rapamycin, on septic death using cecal ligation and puncture (CLP) mice model.
View Article and Find Full Text PDFBartonella effector proteins (named Beps) are substrates of VirB type IV secretion system for translocation into host cells evolved in Bartonella spp. Among these, BepE has been shown to protect cells from fragmentation effects triggered by other Beps and to promote in vivo dissemination of bacteria from the dermal site of inoculation to the bloodstream. Bacterial pathogens secreted effectors to modulate the interplay with host autophagy, either to combat autophagy to escape its bactericidal effect or to exploit autophagy to benefit intracellular replication.
View Article and Find Full Text PDFC-X-C chemokine receptor type 7 (CXCR7) is reported to be overexpressed in tumor endothelial cells (TECs), which are the primary target cells of antivascular chemotherapy. However, the role of CXCR7 in TECs is not fully understood. In the present study, CXCR7 expression was inhibited in TECs derived from hepatocellular carcinoma (HCC) using short hairpin (sh)RNA plasmids to investigate the role of CXCR7 in the regulation of migration and invasion of TECs as well as its underlying mechanisms.
View Article and Find Full Text PDFFor dendritic cells (DCs) to initiate an immune response, their ability to migrate and to produce interleukin-12 (IL-12) is crucial. It has been previously shown that low-dose radiation (LDR) promoted IL-12 production by DCs, resulting in increased DC activity that contributed to LDR hormesis in the immune system. However, the molecular mechanism of LDR-induced IL-12 production, as well as the effect of LDR on DC migration capacity require further elucidation.
View Article and Find Full Text PDFInt J Clin Exp Pathol
September 2017
Pancreatic cancer is one of the most aggressive cancers. Interleukin-22 (IL-22) is a member of IL-10 cytokine family and primarily produced by Th17 cells which were differentiated from CD4 T cells. CD4 T cells play a central role in regulating the immune response and resisting cancer cells.
View Article and Find Full Text PDFSurface texturing-plasma nitriding duplex treatment was conducted on AISI 316 stainless steel to improve its tribological performance. Tribological behaviors of ground 316 substrates, plasma-nitrided 316 (PN-316), surface-textured 316 (ST-316), and duplex-treated 316 (DT-316) in air and under grease lubrication were investigated using a pin-on-disc rotary tribometer against counterparts of high carbon chromium bearing steel GCr15 and silicon nitride Si₃N₄ balls. The variations in friction coefficient, mass loss, and worn trace morphology of the tested samples were systemically investigated and analyzed.
View Article and Find Full Text PDFInt J Clin Exp Pathol
August 2017
Tumor infiltrating lymphocytes in a certain tumor microenvironment are associated with the prognosis of cancer patients. The function of CD4 and CD8 T cells in the microenvironment of pancreatic cancer remains largely unknown. This study aimed to investigate the prognostic value of both CD4 and CD8 TIL subsets and their combined role in pancreatic cancer.
View Article and Find Full Text PDFA novel method for the determination of monoethylglycinexylidide (MEGX) (lidocaine metabolin) in serum using solid phase extraction (SPE) and capillary gas chromatography-mass spectrometry (GC-MS) was established. The serum sample was extracted with a CN-SPE column. An HP-5MS capillary column (15 m x 0.
View Article and Find Full Text PDFHepatobiliary Pancreat Dis Int
February 2008
Background: Caroli's disease, a rare congenital hepatic disease, has a poor prognosis, especially in patients with diffuse dilatation of the bile ducts. But liver transplantation has been a curative option. The aim of this study was to investigate the feasibility and rationality of orthotopic liver transplantation as an indication for patients with diffuse Caroli's disease.
View Article and Find Full Text PDFBackground & Objective: Intrahepatic biliary cystadenocarcinoma (IBC) is a rare intrahepatic malignant tumor which is scarcely reported, and there is relatively little experience in the diagnosis and treatment. This study was to analyze the clinicopathologic features, diagnosis, and treatment of IBC.
Methods: Clinical data of 11 patients with pathologically confirmed papillary IBC, treated between Mar.
Objective: To deduce the region that the geographical species of Lucilia sericata come from and determine the scene of crime (SOC) based on the gene analysis of mtDNA CO II.
Methods: A 635 bp region for CO II of 4 Lucilia sericata (belong to 2 geographical species) were collected and sequenced, compared with the data of GenBank. A neighbour-joining tree with the Tamura and Nei model was constructed by MEGA2.
Zhonghua Gan Zang Bing Za Zhi
June 2006
Objectives: To study the effectiveness of the lidocaine test in evaluating the liver reserve of rats with experimental liver injury in different phases.
Methods: 40 healthy male Wistar rats were divided randomly into experimental and control groups. Rats of the experimental group received subcutaneous CCl4 in oil injection, and rats of the control group received saline injections.