Association between glycemia and outcomes of neonates with hypoxic-ischemic encephalopathy: a systematic review and meta-analysis.

Objectives: The research aimed to provide the most recent and comprehensive analysis and evidence update comparing outcomes in neonatal encephalopathy (NE) based on different glycemia levels.

Patients And Methods: A comprehensive search of Cochrane, PubMed, Embase, Web of Science, CNKI, and Wanfang databases was conducted until September 2023. The purpose was to identify research that examined the effects of hyperglycemia, hypoglycemia, and normoglycemia on NE outcomes.

Factors Contributing to Drug Release From Enteric-Coated Omeprazole Capsules: An In Vitro and In Vivo Pharmacokinetic Study and IVIVC Evaluation in Beagle Dogs.

This study was performed to explore factors influencing the release of the proton pump inhibitor omeprazole from enteric-coated capsules in vitro and absorption in vivo in beagle dogs. Enteric-coated pellets with different enteric coating materials and coating levels were designed and prepared. All self-prepared formulations were characterized in vitro as well as in vivo and compared to the brand and generic commercial products.

[Studies on chemical constituents in root of Phlomis medicinalis I].

Objective: To study the chemical constituents in root of Phlomis medicinalis.

Method: The compounds were isolated and repeatedly purified on macroporous resin, silica gel column chromatography, TLC and Prep-HPLC and the structures were elucidated by physico-chemical properties and NMR spectra.

Result: Eight compounds were obtained and elucidated as 5-Hydroxy-7-methoxy-4, 6-dimethylphthalide (1), 4-hydroxymethyl-2-furaldehyde (2) and six iridoid glucosides: 6-O-acetyl-shanzhiside methyl ester (3), 8-O-acetyl-shanzhiside methyl ester (4), shanzhiside methyl ester (5), sesamoside (6), phloyoside II (7) and dehydropentstemoside (8).

[Infrared spectroscopy technology, one of the faster and more convenient methods to detect the stability of stored Niuxi].

Objective: To detect the change of Niuxi in reserve and establish one easier method of evaluating the quality change of Niuxi.

Methods: Infrared spectroscopy and compare software were used to distinguish the different Niuxi, and simulation testing were used to observe calefactive stability.

Results: There were obvious difference between transmutative and normal Niuxi, and Niuxi had evident change when the temperature above 140 degrees C in the simulation testing.

[Study on sterols and triterpenes from the stems of Akebia quinata].

The ethanol extract from Akebia quinata was seperated by dichloromethane, n-butanol in sequence. Six compounds were isolated and identified as beta-sitosterol (I), delta(5,22) stigmasterol (II), oleanolic acid (III), hederagenin (IV), daucosterol (V), delta(5,22) stigmasterol-3-O-beta-D-glycopyranoside (VI). Compound VI was isolated from Akebia plants for the first time.

[Studies on Niuxi with the method of FT-IR spectroscopy and analyze technology auxiliary].

Objective: To study the genuine of 32 samples of Niuxi from 14 provinces, and compare some samples stored for different time to check the change in the coures of store.

Method: IR spectroscopy and Analyze Technology Auxiliary softeare.

Result: The coefficient correlations had certain difference among these Niuxi from different places.