Efficacy and safety of retention enema with traditional Chinese medicine for ulcerative colitis: A meta-analysis of randomized controlled trials.

Objective: To assess the efficacy and safety of retention enema with traditional Chinese medicine (TCM) for ulcerative colitis (UC) through a meta-analysis of published studies.

Methods: Literatures were retrieved from five electronic databases. Quality evaluation and meta-analysis were respectively conducted using the Cochrane collaboration and RevMan5.

Genome Sequencing Technology used to Explore the 6mA Methylation Level of Silent Alpha-Thalassemia in Postmenopausal Women.

Background: Based on whole-genome sequencing technology our aim is to explore the expression of the alpha-thalassemia trait during menopause period at the 6mA methylation site and evaluate the significance in clinical diagnosis.

Methods: In this study, we collected peripheral blood from the women in the postmenopausal period in our hospital and used the method of (ChIP-seq) immunoprecipitation assay combined with next genome sequencing technology to select the 6mA site and differentially expressed genes and KEGG pathways and thereby investigate the clinical significance of the 6mA methylation site in women with thalassemia.

Results: A total of 38,879 methylation sites were selected, covering a wide range of CpG island and reference sequence genes.

Efficacy of apatinib in advanced hepatocellular carcinoma with lung metastasis: a retrospective, multicenter study.

Purpose: Lung is the most common extrahepatic metastatic site for patients with advanced hepatocellular carcinoma (HCC) and has a worse prognosis than intrahepatic metastasis. Apatinib is a receptor tyrosine kinase inhibitor that is promising for HCC treatment. We investigated whether apatinib is particularly effective for advanced HCC with lung metastasis.

Efficacy of traditional Chinese medicine for chronic gastritis: A meta-analysis of randomized controlled trials.

Background: To systematically evaluate efficacy of traditional Chinese medicine (TCM) in treating chronic gastritis (CG).

Methods: Data sources from PubMed, Embase, Springer Link, China National Knowledge Infrastructure, Chinese Scientific Journals Database, Chinese Biomedicine Database, and Wan-fang database were searched up to July 5, 2018. Review Manager software version 5.

Columbamine suppresses hepatocellular carcinoma cells through down-regulation of PI3K/AKT, p38 and ERK1/2 MAPK signaling pathways.

Hepatocellular carcinoma (HCC) as primary liver cancer in adults is the most common cause led to internal cirrhosis responsible for patients' death, which resulted in nearly a million deaths worldwide on both males and females in the developing and developed countries. Unfortunately, up to date, there are no highly effective treatment of medicine on HCC as lack of comprehensive cellular and molecular mechanism. According to the sources of human ancient history of medicine, traditional medicine could provide unique treatment to discontinue the challenging HCC.

IL-17A inhibits autophagic activity of HCC cells by inhibiting the degradation of Bcl2.

Hepatocellular carcinoma (HCC) is associated with poor prognosis due to many unknowns about its inflammatory microenvironment. As a pivotal proinflammatory cytokine, IL-17A exerts a protective effect on the survival and function of HCC cells. It is widely accepted that IL-17A plays an important role in regulating autophagy.

Seed-Mediated Growth of Silver Nanocubes in Aqueous Solution with Tunable Size and Their Conversion to Au Nanocages with Efficient Photothermal Property.

Two seed-mediated approaches for the growth of silver nanocubes in aqueous solution have been developed. Addition of a silver-seed solution to a mixture of cetyltrimethylammonium chloride (CTAC), silver trifluoroacetate, and ascorbic acid and heating the solution at 60 °C for 1.5 h produces uniform Ag nanocubes with tunable sizes from 23 to 60 nm by simply adjusting the volume of silver-seed solution introduced.

An in-vitro animal experiment on metal implants' thermal effect on radiofrequency ablation.

Background: To explore metal implants' thermal effect on radiofrequency ablation (RFA) and ascertain distance-thermal relationship between the metal implants and radiofrequency (RF) electrode.

Methods: Metal implants models were established in seven in-vitro porcine livers using silver clips or 125I seeds. RFA were conducted centering the RF electrode axis1 cm away from them, with one side containing a metal implants model the test group and the other side the control group.

[Long-term results of surgical treatment of stomach cancer: clinical experience of forty years from Sun Yat-sen University Cancer Center].

Objective: To investigate the approaches to improve therapeutic effect of stomach cancer by analysis of the long-term results of surgical treatment of this disease.

Methods: Prognostic factors of stomach cancer were analyzed by Cox multivariate regression model based on clinical data of 2561 stomach cancer cases who underwent surgical treatment from 1964 to 2004 at Sun Yat-sen University Cancer Center. Survival rates were calculated by life table method.