Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis.

Defining the trajectory of cells during differentiation and disease is key for uncovering the mechanisms driving cell fate and identity. However, trajectories of human cells remain largely unexplored due to the challenges of studying them with human samples. In this study, we investigate the proteome trajectory of iPSCs differentiation to hepatic stellate cells (diHSCs) and identify RORA as a key transcription factor governing the metabolic reprogramming of HSCs necessary for diHSCs' commitment, identity, and activation.

The Self-perceived Mental Health Status and Factors That Influence the Mental Health of Chinese Submariners in the South China Sea: A Cross-sectional Study.

Introduction: To assess the self-perceived mental health of soldiers and officers in the submarine force in the South China Sea, the result of this investigation was compared to the Chinese military male norms, and the factors that influence their mental health was further explored.

Materials And Methods: A total of 580 male submariners agreed to participate. In the final analysis, 511 valid questionnaires were included; 69 incomplete questionnaires were excluded.

Injury Patterns and Medical Evacuation of Patients in Chifeng Tornado in China, August 11, 2017.

Objectives: To study injury patterns and medical rescue operations related to tornadoes that occur in rural areas, this study investigated the data pertaining to the 2017 Chifeng tornado (China).

Methods: Medical records of 52 tornado-related patients were investigated. Data were collected from 3 local hospitals that received all the tornado victims.

Hospitalization Costs and Length of Stay in Chinese Naval Hospitals Between 2008 and 2016 Based on Influencing Factors: A Longitudinal Comparison.

Introduction: A retrospective review conducted in three hospitals of Guangdong and Hainan, China. To analyze the variation tendency of mean hospitalization costs and length of stay (LOS) in naval hospitals over nine years, paying special attention to the factors affecting hospitalization costs and LOS to provide a reference base for health resource allocation in naval hospitals.

Materials And Methods: A total of 21,375 cases of military patients who were hospitalized and treated in three naval hospitals between January 2008 to December 2016 were extracted from the military health system.

A study of polyaniline deposited nanocrystalline diamond films for glucose detection.

Nitrogen-doped nanocrystalline diamond (NCD) films have been deposited on Si substrates in CH4/Ar/N2 gas mixtures by the microwave plasma enhanced chemical vapor deposition (MPECVD) technique. Such films contain very small diamond grains (10 to 30 nm) with high electrical conductivity (126 ohms(-1) cm(-1)) compared to un-doped ones. The films were characterized by scanning electron microscopy (SEM) and Raman spectroscopy.