Publications by authors named "Zhenqiang Chen"

We demonstrate a technique for flexibly controlling subwavelength focusing and scanning, by using the Fourier translation property of a topology-preserved flat lens. The Fourier transform property of the flat lens enables converting an initial phase shift of light into a spatial displacement of its focus. The flat lens used in the technique exhibits a numerical aperture of 0.

View Article and Find Full Text PDF

A diode-pumped Kerr-lens mode-locked laser generating 25 fs pulses at 1080 nm is demonstrated with an Yb-doped compositional mixed calcium aluminate crystal. The Yb:Ca(Gd,Y)AlO laser, which operates at a repetition rate of 65.6 MHz via soft-aperture Kerr-lens mode-locking, is pumped by a spatially single-mode, fiber-coupled diode laser.

View Article and Find Full Text PDF
Article Synopsis
  • A new high-powered, eye-safe KGW Raman laser system has been developed, utilizing a two-crystal Nd:YVO laser driven by an acousto-optic Q-switch.
  • The setup achieves impressive average output powers of 8.1 W at 1496 nm and 9.5 W at 1527 nm, with optical power conversion efficiencies of 12.6% and 14.7%, respectively.
  • The laser generates pulse widths of 4.6 ns and 6.3 ns, with peak powers around 70 kW and 60 kW, while maintaining excellent beam quality across the output power range.
View Article and Find Full Text PDF

Stable vortex lattices are basic dynamical patterns which have been demonstrated in physical systems including superconductor physics, Bose-Einstein condensates, hydrodynamics and optics. Vortex-antivortex (VAV) ensembles can be produced, self-organizing into the respective polar lattices. However, these structures are in general highly unstable due to the strong VAV attraction.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers developed a powerful and precise nanosecond pulsed crystalline Raman laser operating at 1.7 µm using a specialized Nd:YLF laser setup and a unique L-shaped resonator design.
  • The system effectively reduced spectral noise in the emitted light by using a silica etalon, enabling cleaner output at a single longitudinal mode with an average power of up to 2.2 W.
  • By increasing the pump power, the laser transitioned to a multimode operation, achieving a peak power of about 0.8 MW and an average output of 4.8 W, while maintaining high quality in the beam shape.
View Article and Find Full Text PDF
Article Synopsis
  • Crohn's disease (CD) and intestinal tuberculosis (ITB) are often confused for each other, but they require different treatments and prognoses, highlighting the need for accurate diagnosis.
  • A study involving 72 tissue samples used advanced techniques like infrared spectroscopy and machine learning to differentiate between CD and ITB.
  • The developed diagnostic model achieved high accuracy (91.84%), specificity (92.59%), and sensitivity (90.90%), suggesting that this method could effectively distinguish between the two diseases at a molecular level.
View Article and Find Full Text PDF

A four-step synthetic process has been developed to prepare 1,3,5,8-tetrahydroxyxanthone (2a) and its isomer 1,3,7,8-tetrahydroxyxanthone (2b). 25 more xanthones were also synthesized by a modified scheme. Xanthone 2a was identified as the most active inhibitor against both α-glucosidase and aldose reductase (ALR2), with IC values of 7.

View Article and Find Full Text PDF

Objectives: To evaluate the diagnostic performance of urine HIV antibody rapid test kits in screening diverse populations and to analyse subjects' willingness regarding reagent types, purchase channels, acceptable prices, and self-testing.

Designs: Diagnostic accuracy studies PARTICIPANTS: A total of 2606 valid and eligible samples were collected in the study, including 202 samples from female sex workers (FSWs), 304 persons with injection drug use (IDU), 1000 pregnant women (PW), 100 subjects undergoing voluntary HIV counselling and testing (VCT) and 1000 students in higher education schools or colleges (STUs). Subjects should simultaneously meet the following inclusion criteria: (1) being at least 18 years old and in full civil capacity, (2) signing an informed consent form and (3) providing truthful identifying information to ensure that the subjects and their samples are unique.

View Article and Find Full Text PDF

In recent years, advancements in deep Convolutional Neural Networks (CNNs) have brought about a paradigm shift in the realm of image super-resolution (SR). While augmenting the depth and breadth of CNNs can indeed enhance network performance, it often comes at the expense of heightened computational demands and greater memory usage, which can restrict practical deployment. To mitigate this challenge, we have incorporated a technique called factorized convolution and introduced the efficient Cross-Scale Interaction Block (CSIB).

View Article and Find Full Text PDF

A highly powerful nanosecond pulsed deep-red laser was demonstrated by intracavity second-harmonic generation of an actively Q-switched Nd:YLF dual-crystal-based KGW Raman laser in a critically phase-matched lithium triborate (LBO) crystal. The first-Stokes fields at 1461 and 1490 nm driven by the 1314 nm fundamental laser were firstly produced by accessing the Raman shifts of 768 and 901 cm in the KGW crystal, respectively, and thereafter converted to the deep-red emission lines at 731 and 745 nm by finely tuning the phase-matching angle of the LBO crystal and carefully realigning the resonator. Integrating the benefits of the Nd:YLF dual-crystal configuration and the meticulously designed L-shaped resonator, this deep-red laser system delivered the maximum average output powers of 5.

View Article and Find Full Text PDF

We report both theoretically and experimentally a process of optical intrinsic orbit-orbit interaction with a vortex-antivortex structure nested in a freely propagating light field. The orbit-orbit interaction is originating from the coupling between different vortices and antivortices. Based on this process, we reveal the resultant controllable orbital-angular-momentum Hall effect by considering a typical structure, which comprises a vortex-antivortex pair and another vortex (or antivortex) as a controllable knob.

View Article and Find Full Text PDF
Article Synopsis
  • A groundbreaking ten-watt-level eye-safe intracavity crystalline Raman laser has been developed, marking a significant advancement in laser technology.
  • The laser is powered by an acousto-optically Q-switched 1314 nm two-crystal Nd:YLF laser and utilizes the unique bi-axial properties of KGW crystal to operate at diverse dual-wavelength outputs.
  • Under 84.9 W of pumping power, the laser achieved impressive output powers of up to 9.7 W with peak powers reaching approximately 410 kW, while maintaining near diffraction-limited emissions.
View Article and Find Full Text PDF
Article Synopsis
  • A new mixed crystal, Yb:Ca(Gd,Y)AlO, has been developed and tested for its growth and laser capabilities, showing promising results for both continuous-wave and mode-locked operations.
  • The crystal demonstrated a maximum continuous-wave output power of 347 mW with a high slope efficiency of 48.9%, and its emission wavelength can be tuned over a wide range of 90 nm.
  • In mode-locked operation, the crystal produced soliton pulses as short as 35 femtoseconds at a wavelength of 1059.8 nm, achieving an average output power of 51 mW and the potential for higher power with slightly longer pulse durations.
View Article and Find Full Text PDF

Gram staining can classify bacterial species into two large groups based on cell wall differences. Our study revealed that within the same gram group (gram-positive or gram-negative), subtle cell wall variations can alter staining outcomes, with the peptidoglycan layer and lipid content significantly influencing this effect. Thus, bacteria within the same group can also be differentiated by their spectra.

View Article and Find Full Text PDF

The self-healing phenomenon of structured light beams has been comprehensively investigated for its important role in various applications including optical tweezing, superresolution imaging, and optical communication. However, for different structured beams, there are different explanations for the self-healing effect, and a unified theory has not yet been formed. Here we report both theoretically and experimentally a study of the self-healing effect of structured beams in lenslike media, this is, inhomogeneous lenslike media with a quadratic gradient index.

View Article and Find Full Text PDF

Rabi oscillation has been proven to be one of the cornerstones of quantum mechanics, triggering substantial investigations in different disciplines and various important applications both in the classical and quantum regimes. So far, two independent classes of wave states in the Rabi oscillations have been revealed as spin waves and orbital waves, while a Rabi wave state simultaneously merging the spin and orbital angular momentum has remained elusive. Here we report on the experimental and theoretical observation and control of spin-orbit-coupled Rabi oscillations in the higher-order regime of light.

View Article and Find Full Text PDF

We report on a high-repetition-rate and high-beam-quality all-solid-state nanosecond pulsed deep-red laser source by intracavity second harmonic generation of the actively Q-switched Nd:YVO/KGW Raman laser. The polarization of the 1342 nm fundamental laser was aligned with the Ng and Nm axes of KGW crystal for accessing the eye-safe Raman lasers at 1496 and 1526 nm, respectively. With the aid of the elaborately designed V-shaped resonator and the composite Nd:YVO crystal, excellent mode matching and good thermal diffusion have been confirmed.

View Article and Find Full Text PDF

An unprecedented coronavirus disease 2019 (COVID-19) wave occurred in China between December 2022 and January 2023, challenging the efficacy of the primary series of COVID-19 vaccines. The attitudes toward future COVID-19 booster vaccines (CBV) after the massive breakthrough infection among healthcare workers remain unknown. This study aimed to explore the prevalence and determinants of future CBV refusal after the unprecedented COVID-19 wave among healthcare workers.

View Article and Find Full Text PDF

Multi-physics coupling, composed of an intense THz laser and electric field, serves as a new approach to realize the ultrahigh-level enhancement on third-harmonic generation (THG) of cubic quantum dots (CQDs). The exchange of quantum states caused by anticrossing of intersubbands is demonstrated by the Floquet method and finite difference method with the increasing laser-dressed parameter and electric field. The results show that the rearrangement of the quantum states excites the THG coefficient of CQDs four orders of magnitude higher than that achieved with a single physical field.

View Article and Find Full Text PDF

High beam quality 588 nm radiation was realized based on a frequency-doubled crystalline Raman laser. The bonding crystal of YVO/Nd:YVO/YVO was used as the laser gain medium, which can accelerate the thermal diffusion. The intracavity Raman conversion and the second harmonic generation were realized by a YVO crystal and an LBO crystal, respectively.

View Article and Find Full Text PDF

We demonstrate the first multi-segmented Nd:YLF laser, to the best of our knowledge. The multi-segmented crystal was designed to straightforwardly aim for the minimum thermal stress without sacrificing the overall laser efficiency, with the influence of the pump beam waist position considered in particular. Integrating the enhanced thermo-mechanical resistance of multi-segmented crystal and the alleviated heat load of low quantum defect pumping, this end-pumped 1314 nm Nd:YLF laser system delivered a maximum continuous-wave output power of up to 35.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers developed a wavelength-selectable deep-red laser using a Nd:YLF/KGW Raman laser, driven by a 1314 nm acousto-optic Q-switched laser.
  • The setup generated two first-Stokes waves and employed a bismuth borate (BIBO) crystal for frequency conversion, producing four deep-red emissions at 692, 698, 731, and 745 nm.
  • The system achieved average output powers ranging from 2.4 to 3.6 W, with high peak powers and short pulse durations, indicating its reliability for multi-wavelength deep-red laser applications.
View Article and Find Full Text PDF

Concentration-dependent carbon dot (CD) fluorescence was developed and utilized alongside hyperspectral microscopy as a specific labeling and identification technique for bacteria. Staining revealed that the CD concentration within cells depended on the characteristic intracellular environment of the species. Therefore, based on the concentration dependence of the CD fluorescence, different bacterial species were specifically labeled.

View Article and Find Full Text PDF

When it comes to the high-spatial-frequency electromagnetic waves, we usually think of them as the evanescent waves which are bounded at the near-field surface and decay along with propagation distance. A conventional wisdom tells us that the high-spatial-frequency waves cannot exist in the far field. In this work, we show, however, that these high-spatial-frequency waves having wavenumbers larger than the incident one can propagate freely to the far-field regions.

View Article and Find Full Text PDF

The coupling of intense laser field and electric field serves as a new method to achieve the desired electronic states, optical absorption coefficients and refractive index changes of cubic quantum dot for the first time, to the best of our knowledge. The stationary Schrödinger equation was derived and calculated by means of the Kramers-Henneberger transformation, the non-perturbative Floquet method, and the finite difference method. The energy-level anticrossing is activated by multi-physical field to transform suitable quantum states, resulting in the multiple-polarization-selective absorption and refractive index changes.

View Article and Find Full Text PDF