Background: Persistent primitive trigeminal artery variant (PPTAv) is a rare remnant of the primitive intracranial embryonic anastomotic arteries, and its persistence has an unknown etiology. Trigeminal neuralgia attributed to a PPTAv passing through Meckel's cavity is extremely uncommon.
Case Presentation: A 73-year-old woman presented with right-sided facial pain for 10 years that had failed to respond to medication.