Synopsis of recent research by authors named "Zhenou Sun"
- Zhenou Sun's research primarily focuses on the interplay between immune cell function and cancer, investigating how specific compounds can modulate immune responses and cancer growth through mechanisms like ferroptosis and immune checkpoint regulation.
- Key findings include the role of 18β-glycyrrhetinic acid in protecting immune cells from ferroptosis to enhance immune responses against tumors, as well as the disruptive effects of delta-tocotrienol on PD-L1 glycosylation, which reverses immune suppression in cancer.
- Sun's studies also highlight the dual roles of different vitamin E isoforms in cancer biology, demonstrating that while α-tocopherol may promote tumorigenesis, β-tocotrienol exhibits anti-cancer activity by inhibiting PD-L1 expression and related signaling pathways.*
