Publications by authors named "Zhenli Chen"
Article Synopsis
- The study aimed to create interpretable machine learning models using real-world electronic medical record data to diagnose Kawasaki disease and identify important risk factors.
- Conducted with data from 4087 pediatric patients, multiple machine learning models were tested, with the Explainable Boosting Machine (EBM) showing the best performance and interpretability for diagnosis.
- Key indicators like platelet distribution width and erythrocyte sedimentation rate were highlighted as significant predictors in diagnosing Kawasaki disease, showcasing the models' potential for improving early detection.
Background: There are various differences in response to different antipsychotics and antioxidant defense systems (ADS) by sex. Previous studies have shown that several ADS enzymes are closely related to the treatment response of patients with antipsychotics-naïve first-episode (ANFE) schizophrenia.
Objective: Therefore, the main goal of this study was to assess the sex difference in the relationship between changes in ADS enzyme activities and risperidone response.
In order to understand the impacts of dielectric barrier on the discharge characteristics of a nanosecond pulsed surface dielectric barrier discharge (NS-DBD), the effects of dielectric constant and dielectric barrier thickness are numerically investigated by using a three-equation drift-diffusion model with a 4-species 4-reaction air chemistry. When the dielectric constant increases, while the dielectric barrier thickness is fixed, the streamer propagation speed (), the maximum streamer length (), the discharge energy ( Q D _ e i ), and the gas heating ( Q G H ) of a pulse increase, but the plasma sheath thickness (), the fast gas heating efficiency η , and the charge densities on the wall surface decrease. When the dielectric barrier thickness increases, while the dielectric constant is fixed, , , Q D _ e i , and Q G H of a pulse decrease, but , η , and the charge densities on the wall surface increase.
View Article and Find Full Text PDFAim: Abnormally high levels of homocysteine (Hcy) are associated with autism spectrum disorder. Betaine is a methyl group donor in Hcy metabolism, and is known to prevent noxious Hcy accumulation. This study explored whether betaine could influence Hcy metabolism in a mouse model of autism and ameliorate behavioral abnormalities.
View Article and Find Full Text PDFObjective: Questions exist regarding the causal relationship between malnutrition and stroke outcomes. This study aimed to determine whether nutritional status changes or malnutrition during hospitalisation could predict 3-month outcomes in acute stroke patients.
Methods: During a 10-month period, patients who suffered their first stroke within 7 days after stroke onset were included in this prospective multi-centre study.
Background: In previous studies, the expression and localization characteristics of duck plague virus (DPV) gE protein have been described in cultured cells, but the properties of DPV gE protein have not been reported in vivo. Immunofluorescence analysis had been used for the detection of virus antigen, but there was no report on the use of this technique for the detection of DPV gE. In this study, we investigated the distribution of DPV gE protein on DPV-infected ducks using polyclonal antibody raised against the recombinant His-gE fusion protein by indirect immunofluorescence assay (IFA).
View Article and Find Full Text PDFObjective: To investigate the detection rate of malnutrition among post-stroke patients in community hospitals and unravel the relevant factors that precipitate malnutrition after stroke.
Methods: Based on 438 post-stroke patients who were admitted in community hospitals, we examined the demographic characteristics, the nutritional indices and the possible malnutrition related factors through a cross-sectional study.
Results: The detection rate of malnutrition among post-stroke patients was 52.
Objective: To discuss the short-term effects of early naso-gastric nutrition after acute stroke.
Methods: In a prospective non-randomized controlled design, 146 stroke patients with dysphagia were included. 75 patients in the intervention group received standard naso-gastric nutrition and 71 patients in the control group and received feeding supervised by family members.