Modulation Signal Recognition of Underwater Acoustic Communication Based on Archimedes Optimization Algorithm and Random Forest.

This paper researches the recognition of modulation signals in underwater acoustic communication, which is the fundamental prerequisite for achieving noncooperative underwater communication. In order to improve the accuracy of signal modulation mode recognition and the recognition effects of traditional signal classifiers, the article proposes a classifier based on the Archimedes Optimization Algorithm (AOA) and Random Forest (RF). Seven different types of signals are selected as recognition targets, and 11 feature parameters are extracted from them.

Berberine promotes XIAP-mediated cells apoptosis by upregulation of miR-24-3p in acute lymphoblastic leukemia.

Background: Berberine (BBR) has gained considerable attention because of its anti-tumor activity. BBR can induce apoptosis of acute lymphoblastic leukemia (ALL) cells through the MDM2/p53 pathway. However, the effects of BBR on those ALL patients with p53 deficiency remain unclear.

MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.

Aims: Berberine (BBR) is reported to induce apoptosis and inhibit migration of leukemic cells, but the underlying pharmacological mechanisms have not been fully revealed. This study aims to investigate the possible mechanisms from the perspective of autophagy.

Main Methods: P-53-null leukemic cell lines Jurkat and U937 were used for the in vitro study.