Publications by authors named "Zhenjiang Chen"

Soil microorganisms are critical to the occurrence of (Chinese ), a medicinal fungi used in Traditional Chinese Medicine. The over-collection of Chinese has caused vegetation degradation and impacted the sustainable occurrence of . The effects of Chinese collection on soil microorganisms have not been reported.

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Article Synopsis
  • - The studied clavicipitaceous fungus provides stress protection to drunken horse grass, leading to significant changes in the plant's associated bacterial communities when ammonium nitrogen is applied.
  • - Endophyte-infected plants exhibited greater microbial and metabolic alterations compared to uninfected plants, with increased bacterial diversity and changes in root metabolites under nitrogen treatment.
  • - A complex relationship was identified between the root microbiome and metabolites, highlighting the influence of endophyte infection on bacterial community composition and metabolite abundance, particularly for metabolites linked to nutrient metabolism.
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The present study provides a detailed analysis of the chloroplast genome of . The genome consisted of a total of 149,428 bp and four distinct regions, including a large single-copy region (81,329 bp), a small single-copy region (17,261 bp), and an inverted repeat region (25,419 bp). The genome contained 112 genes, including 78 protein-coding genes, 30 tRNA genes, and 4 rRNA genes, and some exhibited duplication in the inverted repeat region.

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In this study, wild barley () infected (E+) and uninfected (E-) by were used for hydroponic experiments during the seedling stage. Various attributes, such as the effect of fungal endophyte on the growth and development of wild barley, the absorption of cadmium (Cd) and mineral elements (Ca, Mg, Fe, Mn, Cu, Zn), subcellular distribution, and chemical forms were investigated under CdCl stress. The results showed that the fungal endophy significantly reduced the Ca content and percentage of plant roots under Cd stress.

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Article Synopsis
  • Researchers are studying how MDANP can help prevent a serious gut problem called necrotizing enterocolitis (NEC) that affects newborns.
  • They tested MDANP, a special peptide found in human milk, in mice to see if it could protect against NEC by reducing cell death in the gut.
  • Results showed that MDANP works by interfering with a stress signaling pathway, helping to keep gut cells healthy and alive during NEC.
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Background: To determine whether early neutrophil, lymphocyte, and platelet ratio (NLPR), neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR), calculated based on easily available parameters in complete blood count, are associated with the development of acute kidney injury (AKI) and mortality during neonatal intensive care unit (NICU) stay, and to evaluate whether these ratios could act as a predictor of AKI and mortality in neonates.

Methods: The pooled data of 442 critically ill neonates from our previously published prospective observational studies of urinary biomarkers were analyzed. Complete blood count (CBC) was measured on NICU admission.

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In view of the devastating impact of neonatal necrotizing enterocolitis (NEC) on newborns, the research on its intervention is particularly important. Although exosomes from human amniotic fluid stem cells (AFSC) and human breast milk (HBM) can protect against NEC, their mechanisms remain unclear. Here, we intend to compare the intervention effects of two types of exosomes on NEC mouse model and reveal their respective regulatory mechanisms.

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Photodynamic therapy (PDT) has been widely used in preclinical trials for treating various tumors. However, the hypoxic environment of tumors and the limited penetration depth of ultraviolet light severely weaken the PDT effect. To solve the above problems, a near-infrared (NIR) light-triggered oxygen (O) self-supplied phototherapeutic platform (UCNPs/CeO/Ce6/BSA) for amplified PDT performance against solid tumors by alleviating tumor hypoxia has been rationally developed.

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Photodynamic therapy (PDT) for hypoxic tumors has attracted wide attention owing to its noninvasiveness, easy maneuverability, and instantaneity. However, hypoxia in tumors and penetration depth of conventional ultraviolet light has greatly weakened its performance. To solve these problems, under NIR-II light irradiation, squaric acid nanoparticles (SQ NPs) with superior reactive oxygen, especially, hydroxyl radicals (•OH) production performance were first utilized for hypoxic tumor therapy.

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In biological research, rapid wide-field fluorescence lifetime imaging has become an important imaging tool. However, the biological samples with weak fluorescence signals and lower sensitivity often suffer from very low precision in lifetime determinations which restricts its widespread utilization in many bioimaging applications. To address this issue, a method is presented in this paper to substantially enhance the precision of rapid lifetime determination (RLD).

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Analog arithmetic operations are the most fundamental mathematical operations used in image and signal processing as well as artificial intelligence (AI).  In-memory computing (IMC) offers a high performance and energy-efficient computing paradigm. To date, in-memory analog arithmetic operations with emerging nonvolatile devices are usually implemented using discrete components, which limits the scalability and blocks large scale integration.

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Surface-enhanced Raman scattering (SERS) is a powerful analytical method that is especially suitable for the detection of protein molecules. Detection sensitivity of SERS is directly related to the enhancement factor of the substrate, which is dependent on the strength of a local surface electric field generated by surface plasmonic resonance from substrate. In this study, an electromagnetic induced transparency like (EIT-like) metamaterial was used as the SERS substrate.

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Hydroponic Hordeum brevisubulatum (wild barley) was used as material in the greenhouse to study the effects of endophyte infection on plant growth, Cd absorption and transport, subcellular distribution, and Cd chemical forms under CdCl2 stress. Endophytic fungi respond positively to chlorophyll content and photosynthetic efficiency under Cd stress. The order of Cd absorption in different parts of the plant was: roots > stems > leaves.

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is an important source of feed and forage for livestock, and of food and drink for humans, but its utilization rate is lower than that of other cereal crops, thus it is crucial to improve barley agronomic traits and production. is an endophyte that was isolated from wild barley (). Previous studies have found that can indirectly influence the growth of host plants by affecting soil chemical characteristics, the microbial community, and by producing a range of secondary metabolites.

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is a salt tolerant forage, which plays an important role in improving saline-alkali land and animal husbandry alkali-saline grassland. has been gradually domesticated as an ornamental grass due to its special flower color. However, no domesticated varieties of plant have been reported worldwide.

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endophytes are biotrophic fungi that establish mutualistic symbiotic relationship with grasses and affect performance of the host under different environments. Wild barley () is an important forage grass and often infected by  , thus showing tolerances to stresses. Since the plant growth correlates with both microbial infection and nutrient stoichiometry, this study was performed to investigate whether the function of   endophyte to improve host growth depend upon the nitrogen (N), phosphorus (P) fertilization.

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Activatable phototherapeutic agents (PTA) in one system with synergistic gas therapy (GT) and photothermal therapy (PTT) hold great promise for highly efficient tumor treatments. In this study, an activatable multifunctional platform with photothermal conversion "turn on" features via nitric oxide (NO) release for synergistic GT and PTT was rationally designed using an aryl N-nitrosamine (NO-donating unit) functionalized aza-BODIPY framework (S-NO). As expected, after NO release from S-NO, the product (Red-S) showed obviously enhanced heat production performance under a longer excited wavelength via improved near-infrared light absorption and decreased fluorescence emission.

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This article reports the complete chloroplast genome of Achnatherum inebrians, a poisonous herb that is widely distributed in the rangelands of Northern China. The genome is 137 714 bp in total and consists of a large single-copy (81 758 bp) region and small single-copy (12 682 bp) region separated by a pair of inverted repeats (21 637 bp). The genome contains 130 genes, including 84 protein-coding genes, 38 tRNA genes and 8 ribosomal RNA genes, and the guanine + cytosine content is 36.

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The complete circular chloroplast (cp) genome of wild Bowden was sequenced and reported in this study. The complete chloroplast genome of wild was 12,753 bp in length, including a pair of inverted repeat regions (IRA/IRB) of 21,587 bp separated by one small single-copy (SSC) region of 12,753 bp and one large single-copy (LSC) region of 81,138 bp. A total of 133 genes, including 85 protein-coding genes (PCGs), 40 transfer RNA genes, and 8 ribosomal RNA genes were predicted from the cp genomes.

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Background: The aim to develop a highly stable near-infrared (NIR) photoinduced tumor therapy agent stems from its considerable potential for biological application. Due to its long wavelength, biological imaging exhibits a high signal-to-background ratio, deep tissue penetration and maximum permissible light power, which can minimize damage to an organism during photoinduced tumor therapy.

Results: A class of stable NIR-II fluorophores (NIR998, NIR1028, NIR980, NIR1030, and NIR1028-S) based on aza-boron-dipyrromethene (aza-BODIPY) dyes with donor-acceptor-donor structures have been rationally designed and synthesized by harnessing the steric relaxation effect and intramolecular photoinduced electron transfer (IPET).

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Objective: Obstructive sleep apnea hypopnea syndrome (OSAHS) and non-alcoholic fatty liver disease (NAFLD) are both strongly associated with obesity. Whether OSAHS is an independent risk factor for liver injury or not is uncertain. To assess the hypothesis that OSAHS is associated with liver injury independent of obesity.

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Objective: To offer scientific basis of distinguish p recious animal TCM.

Method: Molecular weights of the proteins were measured by modified sodium dodecyl sulphate-polyaerylamide gel eleetrophoresis (SDS-PAGE).

Results: The bands were always quite distinct.

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