Zn improves sepsis-induced acute kidney injury by upregulating SIRT7-mediated Parkin acetylation.

Zn levels are reported to be correlated with kidney function. We explored the significance of Zn in sepsis-induced acute kidney injury (SI-AKI) through the regulation of sirtuin 7 (SIRT7) activity. The sepsis rat model was established by cecal ligation and perforation (CLP) and intraperitoneally injected with ZnSO or SIRT7 inhibitor 97491 (SIRT7i), with renal tubular injury assessed by hematoxylin and eosin staining.

Assessment of heavy metals contamination and water quality characterization in the Nanming River, Guizhou Province.

The analysis to assess the water quality and potential ecological risks in sediments was carried out by means of the distribution characteristics of nutrient properties and heavy metals in water, and heavy metals in sediments from the Nanming River. The results from nutrient properties demonstrated that the majority of TN and TP exceeded the permissible limit and concentrated within the study area. The concentrations of heavy metal in water were lower than the permissible limits but may pose potential threat to aquatic ecosystems.

Research Progress of Mercury Bioaccumulation in the Aquatic Food Chain, China: A Review.

Research on mercury (Hg) in aquatic ecosystems in China has focused mainly on fish, with little research on the base of the food chain and Hg bioaccumulation mechanisms. This paper summarizes research progress pertaining to the characteristics, current status, and trends of Hg accumulation in the aquatic food chain in China, analyzes the effects of human activities on the transmission and accumulation of Hg in aquatic food chains, and assesses their risks to human and ecosystem health. A comparison of fish samples in China between 2000 and 2018 indicates that their total Hg content remains at relatively safe levels.