Identification of novel umami peptides from yeast extract and the mechanism against T1R1/T1R3.

Yeast extract was separated by using ultrafiltration, gel filtration chromatography, and preparative high-performance liquid chromatography for analyzing the umami mechanism. 13 kinds of umami peptides were screened out from 73 kinds of peptides which were identified in yeast extract using nanoscale ultra-performance liquid chromatography-tandem mass spectrometry and virtual screening. The umami peptides were found to have a threshold range of 0.

Indole-Based Aza[n]helicenes (n=5, 6) with Violet-Blue Fluorescence and Two-Photon Absorption (TPA).

A series of indole-based helicenes, namely, 15-hexyl-15H-tetraphenyl[1,2-e]indole (HTPI), 14-hexyl-14H-benzo[4',5']thieno [2',3':7,8]naphtha[1,2-e]indole (HBTNI), 7-hexyl-7H-indolo[5,4-k] phenanthridine (HIPD) and 3-hexyl-3H-phenanthro[4,3-e]indole (HPI) were successfully synthesized by three- or four-step reactions. They exhibited good solubility and high thermal stability of T =247, 388, 294 and 251 °C, respectively. These compounds emit violet-blue light with maximum emission peaks at 415, 397, 397 and 391 nm in hexane.

Crystal structure of the lead-containing organic-inorganic hybrid: (CHN)[PbI(DMSO)]·2DMSO.

The title compound, tris-(1,1'-dibutyl-4,4'-bi-pyridine-1,1'-diium) bis-(dimethyl sulfoxide)di-μ-iodido-tetra-μ-iodido-octa-iodido-tetra-lead(II) dimethyl sulfoxide di-solvate, (CHN)[PbI(CHOS)]·2CHOS, belongs to a class of organic-inorganic hybrid materials with novel functionalities. In this compound, C-H⋯O and C-H⋯I hydrogen-bonding inter-actions, π-π inter-actions, other short contacts and Pb octa-hedral chains are present, extending the crystal structure into a three-dimensional supra-molecular network.

Crystal structure of 5,15-dihexyl-5,15-di-hydro-benzo[2,1-:4,3-']dicarbazole hexane 0.375-solvate.

The title compound, CHN·0.375CH, crystallizes in the monoclinic space group 2/ and has a host-guest structure with the helicene molecules forming a porous structure and mol-ecules of hexane inserted into the holes. The dihedral angles between the two carbazole sections of the right- and left-handed helicenes are 27.