Publications by authors named "Zhengzheng Tao"
Background: The pancreas plays a central role in type 2 diabetes mellitus (T2DM), and its blood flow is usually associated with insulin release demand.
Purpose: To noninvasively assess pancreatic blood flow (PBF) changes and modulation in people with different glucose tolerance following a glucose challenge using ASL MRI.
Study Type: Prospective.
Article Synopsis
- The study explored how TGF-β1, USP7, and YAP contribute to ferroptosis, a form of cell death, in the context of sepsis-induced acute lung injury.
- Findings revealed that TGF-β1 worsened ferroptosis in both cell cultures and animal models, while YAP was found to enhance the activity of protective genes like GPX4 and SLC7A11.
- The research proposed a novel regulatory pathway involving TGF-β1, USP7, LATS1/2, and YAP, suggesting potential therapeutic targets for treating sepsis-related lung damage.
In this study, we outlined the green synthesis of Zinc oxide nanoparticles (ZnO NPs) using the plant-mediated method. Employing the nitrate derivative of Zinc and the extract from the native medicinal plant, Ottonia anisum, the nanoparticles were effectively produced. After obtaining a yellow-colored paste, it was meticulously dried, gathered, and set aside for subsequent examination.
View Article and Find Full Text PDFBackground: Idiopathic pulmonary fibrosis (IPF) is an unrepairable disease that results in lung dysfunction and decreased quality of life. Prevention of pulmonary fibrosis is challenging, while its pathogenesis remains largely unknown. Herein, we investigated the effect and mechanism of long non-coding RNA (lncRNA) /Antisense RNA in the pathogenesis of pulmonary fibrosis.
View Article and Find Full Text PDFMultifunctional nanoprobes with tumor microenvironment response are playing important roles in highly efficient theranostics of cancers. Herein, a kind of theranostic nanoprobe was synthesized by coating manganese dioxide (MnO) on the surface of black commercial P25 titanium dioxide (b-P25). The resultant nanoprobe (b-P25@MnO) possessed glutathione (GSH)-responsive magnetic resonance (MR) imaging and enhanced photothermal therapy (PTT).
View Article and Find Full Text PDFObjectives: To assess the value of multiparametric magnetic resonance imaging including intravoxel incoherent motion (IVIM), diffusion tensor imaging (DTI) and blood oxygen level dependent (BOLD) MRI in differentiating the severity of hepatic warm ischemia-reperfusion injury (WIRI) in a rabbit model.
Methods: Fifty rabbits were randomly divided into a sham-operation group and four test groups (n = 10 for each group) according to different hepatic warm ischemia times. IVIM, DTI and BOLD MRI were performed on a 3 T MR scanner with 11 b values (0 to 800 s/mm), 2 b values (0 and 500 s/mm) on 12 diffusion directions, multiple-echo gradient echo (GRE) sequences (TR/TE, 75/2.