Development and preclinical evaluation of a patient-specific high energy x-ray phase sensitive breast tomosynthesis system.

Background: This article reports the first x-ray phase sensitive breast tomosynthesis (PBT) system that is aimed for direct translation to clinical practice for the diagnosis of breast cancer.

Purpose: To report the preclinical evaluation and comparison of the newly built PBT system with a conventional digital breast tomosynthesis (DBT) system.

Methods And Materials: The PBT system is developed based on a comprehensive inline phase contrast theoretical model.