[Clinical effect of allogeneic peroneal bone marrow support combined with plate fixation for the treatment of Neer type Ⅳ proximal humeral fractures].

Objective: To explore clinical effect of allogeneic peroneal bone marrow support combined with plate internal fixation in treating Neer type Ⅳproximal humeral fractures.

Methods: From December 2017 to December 2020,12 patients with Neer type Ⅳ proximal humeral fractures were treated with allogeneic peroneal bone marrow support combined with plate internal fixation,including 7 males and 5 females,aged from 56 to 78 years old;the time from injury to operation ranged from 1 to7 days. Operative time,fracture healing time and complications during follow-up were observed,and clinical efficacy was evaluated by Constant-Murley score at the latest follow-up.

Prognostic significance and survival benefits of postoperative adjuvant chemotherapy in patients with stage IA lung adenocarcinoma with non-predominant micropapillary components.

Background: The prognostic significance of adjuvant chemotherapy (ACT) for patients with stage IA micropapillary non-predominant (MPNP) lung adenocarcinoma (LUAD) remains unknown. This study aimed to investigate the effects of postoperative ACT in patients with stage IA MPNP-LUAD.

Methods: A total of 149 patients with pathological stage IA MPNP-LUAD who underwent surgery at our center were retrospectively analyzed.

Immune evasion in esophageal squamous cell cancer: From the perspective of tumor microenvironment.

Esophageal cancer (EC) is one of the most life-threatening malignancies worldwide. Esophageal squamous cell carcinoma (ESCC) is the dominant subtype, accounting for approximately 90% of new incident EC each year. Although multidisciplinary treatment strategies have advanced rapidly, patients with ESCC are often diagnosed at advanced stage and the long-term prognosis remains unsatisfactory.

Circular RNA circTRPS1-2 inhibits the proliferation and migration of esophageal squamous cell carcinoma by reducing the production of ribosomes.

Circular RNAs play important roles in many cancers, including esophageal squamous cell carcinoma (ESCC), but the precise functions of most circular RNAs are poorly understood. Here we detected significant downregulation of circTRPS1-2 in ESCC based on high-throughput sequencing of three pairs of ESCC tissue and adjacent normal tissue, followed by PCR validation with another 30 tissue pairs. Patients with ESCC whose circTRPS1-2 expression was below the median level for the sample showed significantly shorter median overall survival (13 months) than patients whose circTRPS1-2 expression was above the median (36 months).

Identification of Cell Subpopulations and Interactive Signaling Pathways From a Single-Cell RNA Sequencing Dataset in Osteosarcoma: A Comprehensive Bioinformatics Analysis.

Osteosarcoma is a type of highly aggressive bone tumor arising from primitive cells of mesenchymal origin in adults and is associated with a high rate of tumor relapse. However, there is an urgent need to clarify the molecular mechanisms underlying osteosarcoma development. The present study performed integrated bioinformatics analysis in a single-cell RNA sequencing dataset and explored the potential interactive signaling pathways associated with osteosarcoma development.

[Application of extended trochanter osteotomy wire fixation combined with autologous bone graft in revision of total hip arthroplasty].

Objective: To investigate the clinical effect of using lengthened trochanteric osteotomy wire fixation combined with autologous bone graft in patients undergoing revision total hip arthroplasty.

Methods: From December 2010 to December 2018, 18 patients underwent revision of total hip arthroplasty with extended trochanteric osteotomy wire fixation and autogenous bone graft, including 8 males and 10 females with an average age of (78.89±3.

Effect of different introduction methods of cerium and tin on the properties of titanium-based catalysts for the selective catalytic reduction of NO by NH.

This work investigated the influence of introduction methods of cerium and tin on the physicochemical properties as well as the activity and durability of titanium-based catalysts for the selective catalytic reduction of NO by NH (NH-SCR). Precipitation and impregnation methods were adopted to synthesize a series of cerium-tin-titanium catalysts. These catalysts were characterized by XRD, Raman, N adsorption-desorption, HRTEM, EDS mapping, XPS, H-TPR, NH-TPD and in situ DRIFT.

High Expression of PDE8B and DUOX2 Associated with Ability of Metastasis in Thyroid Carcinoma.

Background: Hormone is an independent factor that induces differentiation of thyroid cancer (TC) cells. The thyroid-stimulating hormone (TSH) could promote the progression and invasion in TC cells. However, few genes related to hormone changes are studied in poorly differentiated metastatic TC.

[A follow up study on the treatment of tibial fractures with intramedullary interlocking nail through the suprapatellar approach].

Objective: To investigate the short-term effect of suprapatellar interlocking intramedullary nail in the treatment of tibial fractures.

Methods: Eighty patients with tibial fractures treated from January 2016 to June 2018 were treated with interlocking intramedullary nail, who were divided into observation group (suprapatellar approach) and control group (patellar ligament approach) according to different surgical approaches. There were 40 cases in the observation group, including 28 males and 12 females, aged 28 to 67 years with a mean of (46.

[Value of quantitative CT in vertebroplasty for osteoporotic fracture combined with scoliosis].

Objective: To investigate the value of lumbar quantitative CT (QCT) in vertebroplasty for osteoporotic fracture combined with scoliosis.

Methods: The clinical data of 60 patients with osteoporotic fractures combined with different degrees of scoliosis treated by vertebroplasty from December 2017 to December 2019 were retrospectively analyzed. There were 18 males and 42 females, aged from 65 to 81 (72.

Hierarchically Structured and Scalable Artificial Muscles for Smart Textiles.

Fiber-based artificial muscles with excellent actuation performance are gaining great attention as soft materials for flexible actuators; however, current advances in fiber-based artificial muscles generally suffer from high cost, harsh stimulation regimes, limiting deformations, chemical toxicity, or complex manufacturing processing, which hinder the widespread application of those artificial muscles in engineering and practical usage. Herein, a facile cross-scale processing strategy is presented to construct commercially available nontoxic viscose fibers into fast responsive and humidity-driven yarn artificial muscles with a recorded torsional stroke of 1752° cm and a maximum rotation speed up to 2100 rpm, which are comparable to certain artificial muscles made from carbon-based composite materials. The underlying mechanism of such outstanding actuation performance that begins to form at a mesoscale is discussed by theoretical modeling and microstructure characterization.

Extrachromosomal circular DNAs are common and functional in esophageal squamous cell carcinoma.

Background: Esophageal squamous cell carcinoma (ESCC) is the leading cause of cancer-related mortality. While recent studies have documented the presence of extrachromosomal circular DNAs (eccDNAs) in various tumors, to date, there have been no studies examining the distribution and function of eccDNAs in ESCC.

Methods: The eccDNAs from three surgically matched ESCC tissue samples were extracted and amplified by rolling circle amplification after removal of linear DNA and mitochondrial circular DNA.

[Effect of double plate technique combined with autogenous iliac bone graft in the treatment of femoral nonunion after intramedullary nailing].

Objective: To investigate the clinical effect of double plate combined with iliac bone graft in the treatment of femoral nonunion after intramedullary nailing.

Methods: From December 2008 to December 2017, double plate combined with autogenous iliac bone graft was used to treat femoral nonunion after intramedullary nailing. There were 11 cases, including 10 males and 1 female, aged 35 to 62 years, and the time from fracture to nonunion was 12 to 20 months.

Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway.

Lung adenocarcinoma (LUAD) is the main subtype of lung cancer. In this study, we found that RBP Mex3a was significantly upregulated in LUAD tissues and elevated Mex3a expression was associated with poor LUAD prognosis and metastasis. Furthermore, we demonstrated that Mex3a knockdown significantly inhibited LUAD cell migration and invasion in vitro and metastasis in nude mice.

Getting insight into the effect of CuO on red mud for the selective catalytic reduction of NO by NH.

A series of copper-modified red mud catalysts (CuO/PRM) with different copper oxide contents were synthesized by wet impregnation method and investigated for selective catalytic reduction of NO by NH (NH-SCR). The catalytic results demonstrated that the red mud catalyst with 7 wt% CuO content exhibited the excellent catalytic performance as well as resistance to water and sulfur poisoning. The red mud support and copper-containing catalysts were characterized by XRF, XRD, N adsorption-desorption, HRTEM, EDS mapping, XPS, H-TPR, NH-TPD and in situ DRIFT.

[Guiding significance of lumbar quantitative computed tomography in percutaneous vertebroplasty for osteoporotic vertebral compression fractures].

Objective: To investigate the guiding significance of lumbar quantitative computed tomography (QCT) in percutaneous vertebroplasty (PKP) for osteoporotic vertebral compression fractures (OVCF).

Methods: The clinical data of 90 patients with OVCF underwent PKP from December 2017 to December 2018 were retrospectively analyzed. There were 24 femalesand66males, withanaverage agedof (74.

Characteristics of SH0-Wave Converted to T(0, 1)-Wave Based on a T-Shaped Plate Wrapped Around a Pipe.

Ultrasonic guided waves are widely used in industrial nondestructive testing for pipes and plates, where pipe waves and plate waves exhibit similar behaviors for some specific modes. This paper investigates the characteristics of an SH0 mode plate wave converted to a T(0, 1) mode pipe wave based on their similar dispersion and wave structure properties. First, the analytical solution is initially proposed to analyze the characteristics of the SH0-wave propagation in a model of arrayed plates coupled to a pipe.

[Comparison of effectiveness between SuperPATH approach and posterolateral approach in total hip arthroplasty].

Objective: To compare the effectiveness between SuperPATH approach and posterolateral approach in total hip arthroplasty (THA).

Methods: Between January 2016 and December 2016, 84 patients with hip disease were included in the study and randomly divided into 2 groups. Forty patients were treated with THA via SuperPATH approach (SuperPATH group), and 44 patients were treated with THA via posterolateral approach (PSA group).

Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids.

There have been no reports describing the effects of cancer cell-derived extracellular vesicles (EVs) on three-dimensional organoids. In this study, we delineated the proneoplastic effects of esophageal adenocarcinoma (EAC)-derived EVs on gastric organoids (gastroids) and elucidated molecular mechanisms underlying these effects. EVs were identified using PKH-67 staining.

The novel fusion transcript NR5A2-KLHL29FT is generated by an insertion at the KLHL29 locus.

Background: Novel fusion transcripts (FTs) caused by chromosomal rearrangement are common factors in the development of cancers. In the current study, the authors used massively parallel RNA sequencing to identify new FTs in colon cancers.

Methods: RNA sequencing (RNA-Seq) and TopHat-Fusion were used to identify new FTs in colon cancers.

Risk factors for recurrence of chronic subdural hematoma after burr hole surgery: potential protective role of dexamethasone.

Objective: Chronic subdural hematomas (CSDHs) are often found in neurosurgery, and display a recurrence rate of up to 37%. This study aimed to determine potential risk factors contributing to unilateral CSDH recurrence, and evaluate the role of postoperative management with dexamethasone (DX) in reducing recurrence.

Methods: Between January 2010 and May 2015, a total of 242 consecutive patients with CSDH treated with burr-hole trephination were included in this study.

A Fast Method to Calculate the Spatial Impulse Response for 1-D Linear Ultrasonic Phased Array Transducers.

A method is developed to accurately determine the spatial impulse response at the specifically discretized observation points in the radiated field of 1-D linear ultrasonic phased array transducers with great efficiency. In contrast, the previously adopted solutions only optimize the calculation procedure for a single rectangular transducer and required approximation considerations or nonlinear calculation. In this research, an algorithm that follows an alternative approach to expedite the calculation of the spatial impulse response of a rectangular linear array is presented.

Mode Conversion Behavior of Guided Wave in a Pipe Inspection System Based on a Long Waveguide.

To make clear the mode conversion behavior of S0-mode lamb wave and SH0-plate wave converting to the longitudinal mode guided wave and torsional mode guided wave in a pipe, respectively, the experiments were performed based on a previous built pipe inspection system. The pipe was wound with an L-shaped plate or a T-shaped plate as the waveguide, and the S0-wave and SH0-wave were excited separately in the waveguide. To carry out the objective, a meander-line coil electromagnetic acoustic transducer (EMAT) for S0-wave and a periodic permanent magnet (PPM) EMAT for SH0-wave were developed and optimized.