Exploring the causal relationship between constipation and ileus: Insights from bidirectional Mendelian randomization and genomic data analysis.

Constipation currently affects approximately 15% of the global population, and contemporary lifestyles are increasing its incidence every year. A significant number of individuals with constipation also experience ileus, a common surgical emergency known for its sudden onset and rapid progression. However, the intricate dynamics of the relationship between constipation and ileus are not well understood.