Multifunctional Photothermal Nanorods for Targeted Treatment of Drug-Resistant Bacteria-Induced Wound Healing.

The challenge of drug-resistant bacteria-induced wound healing in clinical and public healthcare settings is significant due to the negative impacts on surrounding tissues and difficulties in monitoring the healing progress. We developed photothermal antibacterial nanorods (AuNRs-PU) with the aim of selectively targeting and combating drug-resistant (). The AuNRs-PU were engineered with a bacterial-specific targeting polypeptide (UBI) and a bacterial adhesive carbohydrate polymer composed of galactose and phenylboronic acid.