Molecular dynamics study on structural modulation and dyeing property optimization of meta-aramid in a DMSO/electrolyte system.

Meta-aramid (PMIA) fabrics are typically problematic to dye owing to their extremely crystalline structure and high compactness. Herein, Dimethyl sulfoxide (DMSO) and electrolyte as hydrogen bond regulators were selected to improve the dyeability of PIMA dyed with cationic dyes. The PMIA shows both high dyeing and mechanical properties as a result of the synergistic effect of DMSO and electrolyte in the system, which destructs hydrogen bonding networks and increase interaction energy density between dye molecules and PMIA, confirmed by a series of characterization and molecular dynamics simulations.

The protective effect of umbelliferone ameliorates myocardial injury following ischemia‑reperfusion in the rat through suppression NLRP3 inflammasome and upregulating the PPAR-γ.

The present study investigated whether the protective effect of umbelliferone could regulate myocardial injury following ischemia‑reperfusion and improve mitochondrial respiratory function, thereby relieving myocardial injury following ischemia‑reperfusion in rats. In the present study, the extent of inflammation and oxidative stress were analyzed using ELISA. Western blot analysis was employed to investigate the protein expression levels of the PYD domains‑containing protein 3 (NLRP3) inflammasome and peroxisome proliferator‑activated receptor-γ (PPAR‑γ).