Synopsis of recent research by authors named "Zhengkai Chen"
- Zhengkai Chen's recent research focuses on developing innovative synthetic methodologies utilizing CF-imidoyl sulfoxonium ylides as key intermediates, enabling the creation of diverse trifluoromethyl-substituted heterocycles and related compounds.
- His work includes significant advancements in rhodium and palladium-catalyzed transformations, showcasing unique strategies such as C(sp)-H activation and cascade reactions, yielding valuable functionalized materials in moderate to excellent yields.
- The findings emphasize the effectiveness of trifluoroacetimidoyl chlorides and derivatives in facilitating the straightforward synthesis of biologically relevant compounds, which may aid in further pharmaceutical development and structure-activity relationship studies.