Spin-polarized lasing in manganese doped perovskite microcrystals.

Spin-polarized lasers have demonstrated many superiorities over conventional lasers in both performance and functionalities. Hybrid organic-inorganic perovskites are emerging spintronic materials with great potential for advancing spin-polarized laser technology. However, the rapid carrier spin relaxation process in hybrid perovskites presents a major bottleneck for spin-polarized lasing.

Adaptive Helical Chirality in Supramolecular Microcrystals for Circularly Polarized Lasing.

Chiral organic molecules offer a promising platform for exploring circularly polarized lasing, which, however, faces a great challenge that the spatial separation of molecular chiral and luminescent centers limits chiroptical activity. Here we develop a helically chiral supramolecular system with completely overlapped chiral and luminescent units for realizing high-performance circularly polarized lasing. Adaptive helical chirality is obtained by incorporating chiral agents into organic microcrystals.

High expression of antimicrobial peptides cathelicidin-BF in and verification of its activity.

Antibacterial peptides are endogenous polypeptides produced by multicellular organisms to protect the host against pathogenic microbes, they show broad spectrum antimicrobial activities against various microorganisms and possess low propensity for developing resistance. The purpose of this study is to develop recombinant antibacterial peptide cathelicidin-BF by genetic engineering and protein engineering technology, and study its antibacterial activity and , so as to provide reference for the production and application of recombinant antibacterial peptide cathelicidin-BF. In this study, on account of eukaryotic expression system, we expressed and prepared antibacterial peptide cathelicidin-BF.

Exciton-Polaritons and Their Bose-Einstein Condensates in Organic Semiconductor Microcavities.

Exciton-polaritons are half-light, half-matter bosonic quasiparticles formed by strong exciton-photon coupling in semiconductor microcavities. These hybrid particles possess the strong nonlinear interactions of excitons and keep most of the characteristics of the underlying photons. As bosons, above a threshold density they can undergo Bose-Einstein condensation to a polariton condensate phase and exhibit a rich variety of exotic macroscopic quantum phenomena in solids.

Efficacy and Safety of Intrathecal Pemetrexed Combined With Dexamethasone for Treating Tyrosine Kinase Inhibitor-Failed Leptomeningeal Metastases From EGFR-Mutant NSCLC-a Prospective, Open-Label, Single-Arm Phase 1/2 Clinical Trial (Unique Identifier: ChiCTR1800016615).

Introduction: We aimed to evaluate the efficacy and safety of intrathecal pemetrexed (IP) for treating EGFR-mutant leptomeningeal metastases (LMs) from EGFR-mutant NSCLC.

Methods: Patients with EGFR-mutant NSCLC with LM who had failed tyrosine kinase inhibitors were recruited. The dose of IP was escalated from 15 mg to 80 mg using an accelerated titration design in a phase 1 study.

African Swine Fever in a commercial pig farm: Outbreak investigation and an approach for identifying the source of infection.

African Swine Fever (ASF) is a contagious disease of domestic and wild pigs caused by the African Swine Fever Virus (ASFV). The disease has spread globally in recent years with serious economic consequences to pork production. This report describes an ASF outbreak that occurred in a large-scale Chinese commercial pig farm.

Excited state intramolecular single proton transfer mechanism of pigment yellow 101 in solid state: Experiment and DFT calculation.

To investigate fluorescence mechanism of Pigment Yellow 101 (P. Y. 101) in solid state, three aromatic aldehyde azines (1-3) including P.

Controlling Crystal Structures and Multiple Thermo- and Vapochromic Behaviors of Benzimidazole-Based Squaraine Dyes by Molecular Design and Solvent Adjustment.

Organic micro- and nanostructures are expected to be promising candidates for micro- and nanophotonic materials with desirable properties owing to their low cost, flexible molecular design, and tunable self-assembly. Among these candidates, well-known squaraine dyes (SQs) have rarely been investigated because of their nonfluorescent properties in the solid state and because their optical behavior varies with changes in morphology. In this contribution, two novel 1,2-SQs, SQM and SQB, with strong bright-yellow to red fluorescence emission in the crystalline state, were designed and structured at the molecular level and by solvent adjustment.

Induction of auto-anti-idiotypic antibodies specific for antibodies to matrix and envelope glycoprotein from pigs experimentally infected with porcine reproductive and respiratory syndrome virus.

Auto-anti-idiotypic antibodies (Aab-2s) specific for antibodies against envelope glycoprotein GP5 were previously identified in 10 of 12 pigs experimentally infected with porcine reproductive and respiratory syndrome virus (PRRSV). In this study, we report in addition the induction of Aab-2s specific for antibodies against matrix (M) and envelope glycoprotein GP5 antigens in 38 of 47 pigs experimentally infected with PRRSV. Two sets of Aab-2s were induced in the sera, one at 21 days post-infection (DPI) and peaked on 35 DPI and another at 49 DPI and peaked on 77 DPI.

Identification and characterization of auto-anti-idiotypic antibodies specific for antibodies against porcine reproductive and respiratory syndrome virus envelope glycoprotein (GP5).

Auto-anti-idiotypic antibodies (Aab-2s) were detected from pigs experimentally infected with porcine reproductive and respiratory syndrome virus (PRRSV). The Aab-2s were specific against the idiotypic antibodies (Ab-1s) to the envelope glycoprotein GP5 of PRRSV and were detected from serum samples collected between 21 and 98 days post-infection (DPI). Serological characterization indicated that the Aab-2s recognized the idiotype located within or near the antigen-combining sites of the anti-GP5 antibodies, which was shared by both mouse MAb anti-GP5 and swine polyclonal antibodies.