Association of Mite Molecular Sensitization Profiles with Respiratory Allergies and Asthma Control in Children from East China.

Background: Allergic conditions, identified as a significant global health challenge, are profoundly influenced by indoor allergens, especially house dust mites (HDM). Yet the relationship between mite sensitized components and respiratory allergies and asthma control remains poorly understood.

Methods: A cohort of 96 children, either with allergic rhinitis (AR) or rhinitis with asthma syndrome (ARAS), was assessed.

Salivary IgG4 Levels Contribute to Assessing the Efficacy of Subcutaneous Immunotherapy in Children with Asthma or Allergic Rhinitis.

At present, there are no effective, non-invasive, and objective indicators to evaluate the efficacy of pediatric house dust mite (HDM)-specific allergen immunotherapy (AIT). A prospective, observational study was performed in children with () asthma and/or allergic rhinitis (AR). Forty-four patients received subcutaneous -AIT for 2 years, and eleven patients received only symptomatic treatment.

Sensing Shallow Structure and Traffic Noise with Fiber-optic Internet Cables in an Urban Area.

Abstract: Distributed acoustic sensing (DAS) is a novel seismic observation system developed in recent years that can realize ultrahigh density observations and has attracted extensive attention in the field of seismology. DAS uses fiber-optic cables as sensing units, which are easy to incorporate with urban telecommunication fiber-optic cables for seismological observations. Compared with seismometers, DAS has the advantages of being rapidly deployed and recyclable, being able to acquire dense observations at low cost, and convenient data collection.

The Effects and Underlying Mechanisms of Cell Therapy on Blood-Brain Barrier Integrity After Ischemic Stroke.

Ischemic stroke is one of the main causes of mortality and disability worldwide. However, efficient therapeutic strategies are still lacking. Stem/progenitor cell-based therapy, with its vigorous advantages, has emerged as a promising tool for the treatment of ischemic stroke.

NLRP3 inflammasome: a promising target in ischemic stroke.

Background: Recently, several studies have demonstrated that the NLRP3 inflammasome participates in detecting cellular damage and mediating inflammatory responses to aseptic tissue injury following cerebral ischemia. More importantly, blocking or inhibiting NLRP3 inflammasome at multiple levels, such as its expression, assembly and activity, may offer substantial promise to salvage neurological deterioration during ischemic stroke. However, the specific mechanisms about the contribution of NLRP3 to neurovascular damage remain to be established.