Publications by authors named "Zhengben Wu"

Article Synopsis
  • Respiratory structures in vertebrates, like fish gills, are important for gas exchange but also serve as entry points for pathogens; they contain mucosal-associated lymphoid tissue and bacteria essential for fish health.
  • A study on rainbow trout infected with infectious hematopoietic necrosis virus (IHNV) showed a 27% mortality rate in the first two weeks, severe gill damage, increased goblet cells, and strong immune responses.
  • IHNV infection led to significant changes in the microbial community of trout gills, including loss of beneficial bacteria and growth of harmful ones, indicating a secondary bacterial infection alongside the viral infection.
View Article and Find Full Text PDF

Although dielectric barrier discharge (DBD) plasma is a promising technique for CO conversion, realizing CO-to-alcohol is still challenging via the use of HO. Herein, for the first time, efficient CO conversion was achieved via the synergism between the CsSnCl photocatalyst and DBD plasma assisted by HO. The CO conversion ratio of plasma photocatalysis was 6.

View Article and Find Full Text PDF

The immunoglobulin (Ig) is a crucial component of adaptive immune system in vertebrates including teleost fish. Here complete cDNA sequence of IgD heavy chain gene from common carp () was cloned and analyzed. The full-length cDNA of IgD heavy chain gene contained an open reading frame (ORF) of 2460 bp encoding 813 amino acids.

View Article and Find Full Text PDF

The crosstalk between the immune system and microbiota drives an amazingly complex mutualistic symbiosis. In mammals, the upper respiratory tract acts as a gateway for pathogen invasion, and the dynamic interaction between microbiota and mucosal immunity on its surface can effectively prevent disease development. However, the relationship between virus-mediated mucosal immune responses and microbes in lower vertebrates remains uncharacterized.

View Article and Find Full Text PDF

The mucosa of vertebrates is a particularly complex but dynamic environment in which the host constantly interacts with trillions of commensal microorganisms and pathogens. Although the internal and external mucosal microbiomes with immune defense of mammals have been well investigated, the relationship between mucosal microbes and their host's immune responses has not been systematically understood in the early vertebrates. In this study, we compared the composition and distribution of mucosal microbiota in common carp (), and found that there were significant differences of microbiota between in the internal (gut) and external mucosal (buccal mucosa, gills and skin) tissues.

View Article and Find Full Text PDF

The skin of vertebrates is the outermost organ of the body and serves as the first line of defense against external aggressions. In contrast to mammalian skin, that of teleost fish lacks keratinization and has evolved to operate as a mucosal surface containing a skin-associated lymphoid tissue (SALT). Thus far, IgT representing the prevalent Ig in SALT have only been reported upon infection with a parasite.

View Article and Find Full Text PDF

The buccal mucosa (BM) of vertebrates is a critical mucosal barrier constantly exposed to rich and diverse pathogens from air, water, and food. While mammals are known to contain a mucosal associated lymphoid tissue (MALT) in the buccal cavity which induces B-cells and immunoglobulins (Igs) responses against bacterial pathogens, however, very little is known about the evolutionary roles of buccal MALT in immune defense. Here we developed a bath infection model that rainbow trout experimentally exposed to (), which is well known as a mucosal pathogen.

View Article and Find Full Text PDF

Columnaris disease, induced by Flavobacterium columnare, seriously affects the health of freshwater fish species and damages the mucosal tissues, such as the fins, skin, and gills. Teleosts represent the first bony vertebrate to contain both innate and adaptive immune responses against pathogens. So far, three immunoglobulin isotypes (IgM, IgD, and IgT/IgZ) have been identified in teleost fish, and IgT in mucosal tissues of teleost fish was reported to perform a similar function to IgA in mammals during parasitic infection.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionmohkk5jkanl4mioq9jp62ofc2pl69ut4): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once