Identification of Important Modules and Hub Gene in Chronic Kidney Disease Based on WGCNA.

Chronic kidney disease (CKD) is an ongoing deterioration of renal function that often progresses to end-stage renal disease. In this study, we aimed to screen and identify potential key genes for CKD using the weighted gene coexpression network (WGCNA) analysis tool. Gene expression data related to CKD were screened from GEO database, and expression datasets of GSE66494 and GSE62792 were obtained.

[Effect of Nano Zeolites on pH, CEC in Soil and Cd Fractions in Plant and Soil at Different Cadmium Levels].

Soil incubation experiment and pot experiment were carried out to investigate the influence of nano zeolite (NZ) and ordinary zeolite (OZ) on the soil pH, cation exchange capacity, concentration of soil Cd, soil Cd fraction and Cd uptake by Chinese cabbage when exposed to different Cd pollution levels(1, 5, 10 and 15 mg·kg). The results of soil incubation experiment showed that the nano zeolite and ordinary zeolite dose(5, 10 and 20 g·kg) increased the soil pH and cation exchange capacity, and decreased the concentration of soil exchangeable Cd, while increased the concentration of Cd in carbonate, Fe-Mn oxide, organic matter and residual fraction. The lowest EX-Cd was observed in the high nano zeolite (20 g·kg) treatment.

[Effect of Nano Zeolite on Chemical Fractions of Cd in Soil and Uptake by Chinese Cabbage at Different Soil pH and Cadmium Levels].

Incubation experiments were carried out to investigate the influence of different nano zeolite(NZ) and ordinary zeolite(OZ) levels(0, 5, 10 and 20 g·kg) on the fraction distribution coefficient (FDC) of Cd and soil CEC at different soil pH (4, 5, 6, 7 and 8) when exposed to different cadmium(Cd) levels(1, 5, 10 and 15 mg·kg), and pot experiment were carried out to investigate the effects of nano zeolite(NZ) and ordinary zeolite(OZ) on the growth, Cd concentration and Cd accumulation of Chinese cabbage. The results showed that nano zeolite and ordinary zeolite decreased the concentration and FDC of exchangeable Cd (EX-F), and increased the concentration and FDC of carbonate(CAB-F), Fe-Mn oxide(FMO-F), organic matter (OM-F) and residual fraction(RES-F) in incubation experiments. At the end of incubation, the FDC of soil exchangeable Cd decreased from 72.

[Progress on Correlation between the Expression of CDK5 and Brain Injury Time].

Cyclin-dependent kinase 5 (CDK5) is a member of cyclin-dependent kinase family, which does not directly regulate cell cycle. Through phosphorylation of target protein, CDK5 plays an irreplaceable role in the development, reparation and degeneration of neurons. Brain injury refers to the organic injury of brain tissue caused by external force hit on the head.

[Effect of Nano Zeolite on Chemical Fractions of Cd in Soil and Its Uptake by Cabbage].

Incubation experiments were carried out to investigate the influence of different nano zeolite (NZ) and ordinary zeolite (OZ) levels(0, 5, 10 and 20 g · kg⁻¹) on the change trends in fraction distribution coefficient (FDC) of Cd when exposed to different Cadmium (Cd) levels (1, 5, 10 and 15 mg · kg⁻¹), and pot experiments were carried out to investigate their influence on soil Cd fraction and Cd uptake by cabbage. The results in incubation experiments showed that the application of nano zeolite as well as ordinary zeolite effectively decreased the FDC of exchangeable Cd and increased the FDC of Fe-Mn oxide fraction. The FDC of soil Cd from 0 d to 28 d was deceased at first, then increased and tended to be stable, and finally increased.

[Expression of p35 and p25 after Focal Cerebral Contusion in Rat].

Objective: To study the expression of p35 and p25 in rat after focal cerebral contusion and to provide experimental data for estimating brain injury time.

Methods: Fifty adult male SD rats were randomly divided into 0 h, 6 h, 12 h, 24 h, 3 d, 5 d, 7 d, 10 d after focal cerebral contusion, control and sham-operated groups (5 rats each group). The focal cerebral contusion rat model was established.

[Effects of Organic and Inorganic Slow-Release Compound Fertilizer on Different Soils Microbial Community Structure].

As a new style fertilizer, slow-control release fertilizer had been an important subject in recent years, but few researches were about soil microbial community structure diversity. Phospholipid fatty acid method was used to determined the microbial community structure diversity of acid soil and slight alkaline soil applied with slow-release compound fertilizer (SRF), chemical fertilizer (CF) and common compound fertilizer (CCF) at the 10th, 30th, 60th and 90th day under the constant temperature incubation condition. Results indicated that various bacteria (i.

[Effect of exogenous selenium on accumulation and chemical forms of cadmium in cucumber (Cucumis satiuus L.)].

Pot experiments were carried out to investigate the influence of different selenium (Se) levels (0, 0.5 and 1.0 mg x L(-1)) on the plant growth, concentration of malonaldehyde (MDA), activities of antioxidant enzymes, accumulation and chemical forms of cadmium (Cd) in cucumber when exposed to Cd (20 mg x kg(-1)).

[Effects of ryegrass and arbuscular mycorrhiza on activities of antioxidant enzymes, accumulation and chemical forms of cadmium in different varieties of tomato].

Pot experiments were carried out to investigate the effects of ryegrass and arbuscular mycorrhiza on the plant growth, malondialdehyde (MDA), antioxidant enzyme activities of leaf and root, accumulation and chemical forms of cadmium (Cd) in tow varieties of tomato when exposed to Cd (20 mg x kg(-1)). The results showed that dry weights of fruit and plant, and contents of malondialdehyde (MDA) and antioxidant enzyme activities of leaf and root, and concentrations and accumulations of Cd significantly differed between two varieties of tomato. Dry weights of fruit, roots, stem, leaf and plant were increased by single or combined remediation of ryegrass and arbuscular mycorrhiza, while MDA contents and antioxidant enzyme activities of leaf and root reduced.

[Relationship between tumorous stem mustard yield and soil fertility in Fuling, Southwest China].

By combining field investigation and indoor chemical analysis, the relationship between tumorous stem mustard yield and soil fertility factors was investigated in the main planting areas of tumorous stem mustard in Fuling, Southwest China. The results showed that available Ca, Mg, Fe, Mn, Cu and Zn in the soil were rich (3034, 260, 11.2, 26.

[Distribution characteristics of soil cadmium in different textured paddy soil profiles and its relevance with cadmium uptake by crops].

Adopting atomic absorption spectrometry (novAA400), the present study investigated the distribution characteristics of soil cadmium (Cd) in different textured paddy soil profiles under rice-wheat rotation and its correlation with Cd uptake by rice and wheat in Chengdu Plain through repeatedly taking soil and plant samples at the fixed sites in the field. The results revealed that Cd in the paddy soil profiles was mainly concentrated at the plough layer (0-15 cm) that obviously featured 'Cd accumulates towards the rooting layer'. Soil total Cd and available Cd (1 mol x L(-1) MgCl2 extraction) in the profile declined with soil depths and its average values at 30-45 cm only accounted for 47.

[Homer protein expression after focal brain contusion in rats].

Objective: To investigate Homer protein expression after focal brain contusion and explore the relationship between expression and injury time.

Methods: Focal brain contusion in rats was established and Homer protein expression in brain at different injury intervals after contusion was detected by immunohistochemistry and Western blotting.

Results: A small amount of Homer positive expression cells were detected in control group, sham operated group and experimental group (0.

[Ammonia volatilization of slow release compound fertilizer in different soils water conditions].

By using venting method incubation experiment, we studied the ammonia volatilization and kinetics characteristics of uncoated slowed release compound fertilizer (SRF) under different soil water conditions and the growth and nitrogen utilization efficiency of rice in pot experiment. Results indicated that the ammonia volatilization of SRF under waterflooding reached the peak ahead of 3-4 days compared to the moist treatment. The peak and accumulation of ammonia volatilization in the waterflooding treatments were higher than those under the moist condition.

[Preliminary studies on the nutrient characters of different kinds of Chinese goldthread soil].

Objective: To study the changes of nutrient contents in Chinese goldthread soil before and after planting Coptis chinensis.

Method: The soil in Shizhu, Chongqing, was analyzed for nutrient contents.

Result And Conclusion: The results indicated that the preplanted soil was strongly acidic and the levels of organic matter, total nitrogen and potassium were high.