Publications by authors named "Zheng-dao Li"

Article Synopsis
  • The study examines post-traumatic related limb osteomyelitis (PTRLO) in China, revealing a notable increase in infection rates from 0.93% to 2.16% over ten years, with a predominance of monomicrobial infections (82.6%).
  • The research identified significant increases in both Gram-positive (GP) and Gram-negative (GN) pathogens, with the most common strains being Methicillin-sensitive Staphylococcus aureus (MSSA) and Pseudomonas Aeruginosa, respectively.
  • High-risk factors for polymicrobial infections included open fractures, hypoproteinemia, and multiple fractures, emphasizing the need for targeted antibiotic resistance and sensitivity analysis.
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Fecundity in livestock is an economically important complex quantitative trait that is influenced by both genetics and the environment. However, the underlying genetic mechanism of reproductive performance in goats has not been well investigated. To investigate the genomic basis of fecundity in goats, genomic sequencing data of the Jining grey goat (a high prolificacy breed in China) were collected, as well as data for other commonly available goat breeds, and a mass of genomic variants were generated after variation calling.

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Objective: To study DNA quantification and STR typing of samples pre-treated with pyramidon.

Methods: The blood samples of ten unrelated individuals were anticoagulated in EDTA. The blood stains were made on the filter paper.

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Objective: Allogeneic marrow transplantation is a curative therapy for thalassemia, but no more than 30% of patients have HLA-indentical sibling marrow donor. The selection of alternative donors of unrelative marrow and the study on the probability of treating thalassemia major with unrelated donor bone marrow transplantation are of importance.

Methods: Nine children with thalassemia were included in the study, and their gene mutational type were homozygote of thalassemia and double heterozygote, respectively.

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We report our experience in successful unrelated-donor bone marrow transplantation in 2 cases of beta-thalassemia major, which are approved to be the first 2 cases in Asia. The 2 children receiving transplantation of the bone marrow from unrelated donors were diagnosed as having beta-thalassemia major, whose gene mutation type was homozygous and double heterozygote. High-resolution HLA typing found a mismatch with 1 sub-locus in both cases, and red blood cell type was mismatched in 1 case.

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