Publications by authors named "Zheng-Yang Bao"
Obesity is an important risk factor for hypertension. We aimed to investigate the association between different obesity patterns and hypertension risk in a large male population in the US. Male participants from the National Health and Nutrition Examination Survey (NHANES) (2007-2018) were enrolled in this cross-sectional study.
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- Neutrophils are key players in the immune response, and this study aimed to investigate how common neutropenia (low neutrophil count) is in the U.S. using data from the NHANES survey collected between 2011-2018.* -
- The analysis included over 32,000 participants and found that black individuals had significantly lower leukocyte and neutrophil counts compared to white participants, with smokers exhibiting higher counts than non-smokers.* -
- The overall prevalence of neutropenia was estimated at 1.24%, impacting around 35.5 million Americans, and certain groups, such as black individuals, males, and children under 5, showed a higher risk for
The formation of advanced glycation end-products(AGEs) is an important cause of metabolic memory in diabetic patients and a key factor in the formation of atherosclerosis(AS) plaques in patients with diabetes mellitus. Related studies showed that AGEs could disrupt hemodynamic steady-state and destroy vascular wall integrity through the endothelial barrier damage, foam cell(FC) formation, apoptosis, calcium deposition and other aspects. At the same time, AGEs could initiate oxidative stress and inflammatory response cascade via receptor-depended and non-receptor-dependent pathways, promoting plaques to develop from a steady state to a vulnerable state and eventually tend to rupture and thrombosis.
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