Objective: To determine whether the endoplasmic reticulum stress participates into the apoptosis process of the retina during experimental retinal detachment-by detecting the level of mRNA and protein of the GADD153, the marker of endoplasmic reticulum stress.
Methods: Completely random design is applied. Experimental retinal detachment was created in the left eyes of 77 wistar rats by injecting hyaluronic acid into the subretinal space.