Publications by authors named "Zheng-Nan Huang"
Riveting technique in percutaneous balloon compression for trigeminal neuralgia remedy.
Clin Neurol Neurosurg
May 2024
Article Synopsis
- Percutaneous balloon compression (PBC) is a safe and easy treatment for trigeminal neuralgia, which is a type of face pain. It works by pressing on a nerve to stop the pain signals.
- The study tested a new technique called "riveting" to see if pulling an inflated balloon gives better results than the old method.
- Results showed that the riveting technique helped most patients feel better, with 98% improvement, compared to 87% in the old method, and both techniques caused some temporary facial numbness that got better over time.
Objective: Although endoscopic drill has the advantages in manipulation and hemostasis, whose low efficiency and blurred vision reduce the efficacy of lumbar endoscopic unilateral laminotomy with bilateral decompression (LE-ULBD). The present study was designed to evaluate the safety and efficacy of full-visualized trephine/osteotome in the LE-ULBD surgery for severe lumbar stenosis.
Methods: Fifty-seven severe lumbar stenosis patients who underwent LE-ULBD between January 2020 to January 2023 were enrolled, who were divided into drill and visualized trephine groups.
Ten-eleven translocation 1 (TET1) is a member of methylcytosine dioxygenase, which catalyzes 5-methylcytosine (5 mC) to 5-hydroxymethylcytosine (5 hmC) to promote the demethylation process. The dysregulated TET1 protein and 5 hmC level were reported to either suppress or promote carcinogenesis in a cancer type-dependent manner. Currently, the role of TET1 in the development of urinary bladder cancer (UBC) and its underlying molecular mechanisms remain unclear.
View Article and Find Full Text PDF[Investigation of the prevalence of periodontal diseases among naval personnel during prolonged sailing].
Shanghai Kou Qiang Yi Xue
February 2015
Article Synopsis
- The study aimed to investigate how prolonged sailing affects periodontal diseases among naval personnel, focusing on various dental health indices.
- Data was collected from 186 naval personnel before and after their sailing experience, revealing a significant increase in periodontal disease prevalence from 59.7% to 83.3% post-sailing.
- Findings suggest that factors like a restricted diet and poor oral hygiene during extended periods at sea contribute to the deterioration of dental health, highlighting the need for improved oral hygiene education and practices among sailors.
[The effect of different factors on forming-dentin differentiation of rat dental mesenchymal cells].
Shanghai Kou Qiang Yi Xue
December 2014
Purpose: To investigate the effects of combined use of bFGF, IGF1, BMP4 and TGF-β1 on forming-dentin differentiation of rat dental mesenchymal cells (rDMCs).
Methods: Enzyme and differential digestions were performed to isolate and culture rDECs and rDMCs, and immunofluorescence staining against cytokeratin and vimentin were carried out to identify cell sources. Then alizarin red staining and Gomori calcium-cobalt method were used to detect the mineralization ability of rDMCs after mineralized induction.
[The effects of ADAM28 AS-ODN on biological function of human gingival fibroblasts].
Shanghai Kou Qiang Yi Xue
October 2014
Purpose: To study the effects of a disintegrin and metalloproteinase 28 (ADAM28) antisense oligodeoxynucleotide (AS-ODN) on proliferation, differentiation and apoptosis of human gingival fibroblasts (HGFs), and analyze the possible mechanism.
Methods: Cell culture, gene transfection, MTT chromatometry, enzyme dynamics, and flow cytometry (FCM) techniques were used to detect the effects of ADAM28 AS-ODN on biological characteristics of HGFs after transfected into HGFs. The statistical differences were evaluated by SNK test with SPSS 16.
[Effects of ADAM28 AS-ODN on proliferation, differentiation and apoptosis of HPDLSC].
Shanghai Kou Qiang Yi Xue
October 2009
Purpose: To investigate the effects of a disintegrin and metalloproteinase 28(ADAM28) antisense oligodeoxynucleotide (AS-ODN) on proliferation, differentiation and apoptosis of human periodontal ligament stem cell(HPDLSC) and possible mechanism.
Methods: HPDLSC was isolated, cultured in vitro and identified. Synthetic ADAM28 AS-ODN and S-ODN were transfected into HPDLSC, respectively.
[The construction of ADAM28 eukaryotic expression plasmid and expression after transfected into HDFC].
Shanghai Kou Qiang Yi Xue
August 2007
Purpose: To construct a disintegrin and metalloproteinase (ADAM28) eukaryotic expression plasmid and detect the expression of ADAM28 gene in human dental follicle cells (HDFC) after eukaryotic plasmid was transfected into HDFC.
Methods: Gene rebuilt technique was used to construct ADAM28 eukaryotic expression plasmid, cell culture and gene transfection into HDFC mediated by Lipofectamine2000, immunofluorescence, RT-PCR and Western blot were used to detect the expression of ADAM28 in HDFC.
Results: ADAM28 eukaryotic plasmid was constructed, identified successfully and transiently transfected into HDFC for 72 hours.