Nurses' Workplace Social Capital and the Influence of Transformational Leadership: A Theoretical Perspective.

Workplace social capital is the relational network, created by respectful interactions among members of a workforce, can contribute to the formation of a wholesome psychological work environment in an organization. Nurses' workplace social capital is a derivative of the workplace social capital, formed because of the complex interactions among the nursing and between the other healthcare professionals. Transformational leadership is a style of leadership that addresses the emotional wellbeing of its workforce and inspires shared group ethics, norms, and goals.

[Establishment of three-dimensional culture models related to different stages of nasopharyngeal carcinogenesis].

Background & Objective: Since three-dimensional culture simulates in vivo microenvironment better than planar culture, the biological character of cells in three-dimensional culture model are more similar with that of living tissues. This study was to establish three-dimensional culture models that represent different stages of nasopharyngeal caicinogenesis, and provide information to elucidate the related molecular events.

Methods: Non-tumor nasopharyngeal biopsy specimens were used to culture for normal nasopharyngeal epithelial cells.

The effect of p21 antisense oligodeoxynucleotides on the radiosensitivity of nasopharyngeal carcinoma cells with normal p53 function.

Objective: p21(WAF1/CIP1) is transcriptionally activated by p53 and is required for G1 to S phase progression. p21 plays a critical role in DNA repair after DNA damage. Thus, cells with defective p21 may result in an enhancement of radiation induced apoptosis and improved radiosensitivity.

[Effect of EBV encoded BARF1 gene on malignant transformation of human epithelial cell line HBE].

Background & Objective: The BARF(1) (BamHI A right frame1)gene,encoded by Epstein-Barr virus(EBV),may have oncogenic properties,which leaded to immortalization of a monkey kidney epithelial cell line and malignant transformation of human B lymphocytes and murine fibroblasts. This study was designed to evaluate effect of BARF(1) on cell transformation and tumorgenesis on human epithelia and its mechanisms.

Methods: BARF(1) was amplified from B95-8 cell line by polymerase chain reaction (PCR).