Publications by authors named "Zheng-Liang Qiu"
Article Synopsis
- - Enhancers are DNA elements that boost the transcription of genes in specific tissues, and their malfunction can lead to diseases like cancer; recent research highlights their role in regulating microRNAs (miRNAs) across various cancers, revealing complex interactions.
- - A study identified 2,418 proximal and 1,280 distal enhancer-miRNA interactions across 31 types of cancer, showing a strong correlation between miRNA expression and the number of enhancers involved, along with distinct cancer-specific patterns at the tissue level.
- - The analysis found significant differences between enhancers regulating miRNAs and those that do not, in terms of sequence conservation and histone modifications, with a case study linking an enhancer to thyroid cancer survival and gene expression affecting tumor
[Protective effect of HS-6101 on rhesus monkeys with severe hematopoietic acute radiation sickness].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2014
This study was purposed to investigate the protective effects of lipoprotein HS-6101(6101) on rhesus monkey total body irradiated with 7.0 Gy ⁶⁰Coγ-ray. A total of 30 health adult rhesus monkeys were randomly divided into symptomatic therapy (ST), WR2721 and HS-6101 30, 90 and 270 mg/kg groups (n = 6), the rhesus monkeys of each groups were injected with physiological saline 0.
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- Bartonella quintana is a bacterium associated with various diseases in humans, including trench fever, traditionally thought to be limited to human reservoirs.
- Research on macaques in mainland China revealed a significant prevalence of B. quintana infections, particularly in younger monkeys, with 18% of rhesus macaques and 12.7% of cynomolgus macaques testing positive.
- The study also found higher genetic diversity of B. quintana in macaques compared to humans, indicating that trench fever may primarily originate from these nonhuman primate hosts.