Biomarkers for the prediction of major adverse cardiovascular events in patients with acute coronary syndrome.

The aim of this study is to find novel biomarkers for prognosis in patients with acute coronary syndrome (ACS). We enrolled 245 eligible patients with ACS and compared the protein expression between the two groups, with or without major adverse cardiovascular events (MACE). To determine biomarkers for prognosis, we performed mass spectrometry analysis.

[FTIR spectroscopic explorations of freshly resected laryngeal carcinoma tissues].

Objective: To investigate the characteristics of freshly resected laryngeal carcinoma by Fourier transform infrared spectroscopy (FTIR).

Methods: FTIR was applied to the study of the cancerous tissues and adjacent normal tissues in 32 patients.

Results: Compared with pathological diagnosis results, one benign specimen was classified as a malignant, the accuracy was 98.

[Clinical study on the therapeutic effects and mechanism of progesterone in the treatment for acute severe head injury].

Objective: To evaluate the therapeutic effects of Progesterone (PG) on the patients with acute severe traumatic brain injury, and investigate it's neuroprotective mechanisms.

Methods: Fifth-six patients with acute severe traumatic head injury were divided randomly into two groups: 26 cases were treated with PG and 30 cases were control. Neurological outcome of the patients were assessed using Glasgow Coma Scale (GCS), Glasgow Outcome Scale (GOS), verbal and motor functions scale and Karnofsky Performance Scale (KPS).

[Expression of survivin gene and its relationship with expression of p15, p16 proteins in laryngeal squamous cell carcinomas].

Objective: : To investigate the expression of Survivin (SVV) and its relationship with expression of p15, p16 in laryngeal squamous cell carcinoma (LSCC).

Methods: Using strep avidin-biotin complex (SABC) method, we examined the expression of SVV, p15 and p16 gene in 48 LSCC tissus samples, 24 normal laryngeal mucosa tissus samples and 24 normal laryngeal tissus adjacent to the tumors samples.

Results: SVV was expression in 27 of 48 (56.

[Study on the expression of the metastasis suppressor gene KAI1 in laryngeal squamous cell carcinoma].

Objective: To investigate the expression of the metastasis suppressor gene KAI1 in laryngeal squamous cell carcinoma and the relationship between expression of KAI1 and it's role in tumorgenesis and development.

Methods: The sections of 84 samples of primary laryngeal squamous cell carcinoma (PLSCC), 27 samples of laryngeal precancerous lesion (LPL), 10 samples of vocal cords polyp (VCP) and 10 samples of normal laryngeal tissues (NLT) were examined by in situ hybridization for KAI1mRNA.

Results: It was found that 10 samples of NLT and 10 samples of VCP showed strong expression of KAI1, the Integrated A Total of KIA1 in these two types of tissues were 136,206.