Publications by authors named "Zheng-Hao Hua"
Article Synopsis
- Human pharyngeal squamous cell carcinoma (HPSCC) is a common and deadly cancer in the head and neck, often spreading to other regions.
- Fucoxanthin, a compound found in brown algae, shows promise in inhibiting the growth and spread of HPSCC cells in laboratory studies.
- The study found that fucoxanthin affects key pathways in cancer cell behavior, specifically targeting proteins involved in cell proliferation and metastasis, suggesting its potential as a treatment for HPSCC.
This study investigated the mechanism by which fucoxanthin acts as a novel ferroptosis inducer to inhibit tongue cancer. The MTT assay was used to detect the inhibitory effects of fucoxanthin on SCC-25 human tongue squamous carcinoma cells. The levels of reactive oxygen species (ROS), mitochondrial membrane potential (MMP), glutathione (GSH), superoxide dismutase (SOD), malondialdehyde (MDA), and total iron were measured.
View Article and Find Full Text PDFObjective: To observe the pharmacokinetics of adriamycin-adsorbing nanometric activated carbon in intralymphatic chemotherapy.
Methods: Two ml of suspension of activated carbon with the diameter of 21 nm was mixed with adriamycin 5 mg. Eighteen dogs were randomly divided into 6 equal groups.