Design and Synthesis of Novel Diphenyl Ether Carboxamide Derivatives To Control the Phytopathogenic Fungus .

Sclerotinia stem rot (SSR) caused by the phytopathogenic fungus has led to serious losses in the yields of oilseed rape and other crops every year. Here, we designed and synthesized a series of carboxamide derivatives containing a diphenyl ether skeleton by adopting the scaffold splicing strategy. From the results of the mycelium growth inhibition experiment, inhibition rates of compounds and showed more than 80% to control at a dose of 50 μg/mL, which is close to that of the positive control (flubeneteram, 95%).

A new species of the genus Fennah, 1978 from China (Hemiptera, Fulgoroidea, Issidae).

A new species is described and illustrated from southeastern China. The generic characteristics are redefined. A checklist and key to the species of the genus are provided.

Review of the planthopper genus Neohemisphaerius (Hemiptera, Fulgoroidea, Issidae) with description of one new species from China.

The planthopper genus Neohemisphaerius Chen, Zhang & Chang, 2014 (Hemiptera: Fulgoroidea: Issidae) is reviewed to include 3 species: Neohemisphaerius wugangensis Chen, Zhang & Chang, 2014 (China: Hunan), Neohemisphaerius yangi Chen, Zhang & Chang, 2014 (China: Guangdong) and Neohemisphaerius guangxiensis sp. n. (China: Guangxi).

Anti-phytopathogenic activity of sporothriolide, a metabolite from endophyte Nodulisporium sp. A21 in Ginkgo biloba.

Phytopathogenic fungi such as Rhizoctonia solani and Sclerotinia sclerotiorum caused multiple plant diseases resulting in severe loss of crop production. Increasing documents endorsed that endophytes are a striking resource pool for numerous metabolites with various bioactivities such as anti-fungal. Here we reported the characterization and anti-phytopathogenic activity of sporothriolide, a metabolite produced by Nodulisporium sp.

Review of the genus Neotetricodes Zhang et Chen (Hemiptera: Fulgoromorpha: Issidae) with description of two new species.

Two new species of the issid genus Neotetricodes Zhang et Chen (Hemiptera: Fulgoromorpha: Issidae): Neotetricodes longispinus Chang et Chen sp. nov. (China: Yunnan) and Neotetricodes xiphoideus Chang et Chen sp.

Review of the Chinese species of the genus Varma Distant (Hemiptera, Fulgoromorpha, Tropiduchidae), with description of two new species.

Two new species of Varma Distant, 1906, V. falcata Chang & Chen, sp. n.

Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans.

Perturbation of pheromone signaling modulates not only mating but also virulence in Cryptococcus neoformans, an opportunistic human pathogen known to encode three Galpha, one Gbeta, and two Ggamma subunit proteins. We have found that Galphas Gpa2 and Gpa3 exhibit shared and distinct roles in regulating pheromone responses and mating. Gpa2 interacted with the pheromone receptor homolog Ste3alpha, Gbeta subunit Gpb1, and RGS protein Crg1.

[Single-chain urokinase-type plasminogen activator (scu-PA) purification by immuno-affinity chromatography].

The only difference of primary structure between single-chain prourokinase (pro-UK or scu-PA) and two-chain urokinase (UK or tcu-PA) is the cleavage of a single peptide bond (Lys158-Ile159) and transform scu-PA into its active two-chain form. A 13-peptide (Thr-Leu-Arg-Pro-Arg-Phe-Lys-Ile-Ile-Gly-Gly-Glu-Cys), which spans the cleavage peptide bond, was synthesized and linked to KLH (Keyhole limpet hemocyanin). The Balb/c mice were immunized by the conjugated protein with proper adjuvant.