Increased activity of amino acid transporters has been observed in a wide variety of cancers. However, whether amino acid metabolism is related to estrogen receptor-positive (ER) breast cancer has been less well studied. We identified the rate-limiting enzyme involved in amino acid metabolism associated with ER breast cancer by integrating numerous bioinformatics tools and laboratory studies.
View Article and Find Full Text PDFZhongguo Wei Zhong Bing Ji Jiu Yi Xue
December 2009