Publications by authors named "Zheng Y Zhang"
Article Synopsis
- The study aimed to compare survival rates and risk factors between two subtypes of ampullary adenocarcinoma (intestinal and pancreatobiliary) using data from 184 patients who had operations between 2007 and 2018.
- Results showed that the pancreatobiliary subtype had worse outcomes, including larger tumors, higher rates of jaundice and perineural invasion, and more advanced disease stages compared to the intestinal subtype.
- Both subtypes did not benefit from adjuvant chemotherapy, and the pancreatobiliary subtype had higher recurrence rates and poorer overall survival compared to the intestinal subtype.
A case control study including 45 acute pancreatitis and 44 healthy volunteers was performed to investigate the association between intestinal microbial community and acute pancreatitis. High-throughput 16S rRNA gene amplicon sequencing was used to profile the microbiological composition of the samples. In total, 27 microbial phyla were detected and the samples of pancreatitis patients contained fewer phyla.
View Article and Find Full Text PDFBackground & Aims: SIRT1 is a class III histone deacetylase that plays diverse roles in various cancers. However, the clinical significance of SIRT1 in hepatocellular carcinoma (HCC) remains unknown.
Methods: We analysed p53 mutations and the activation of SIRT1 in 252 hepatitis B virus-positive HCC cases.