Publications by authors named "Zheng Cai Lou"

Objective: To compare surgical results of endoscopic myringoplasty using double layer cartilage-perichondrium grafts versus single fascia grafts.

Study Design: Prospective, randomized, controlled.

Setting: University-affiliated teaching hospital.

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Objective: To evaluate the graft success rate and postoperative hearing gain for marginal perforations using endoscopic cartilage myringoplasty with the removal of a small rim of the external auditory canal (EAC).

Study Design: Prospective case series.

Materials And Methods: We performed a prospective study in 41 patients with marginal perforations who underwent endoscopic cartilage myringoplasty with the removal of a small rim of EAC.

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Introduction: Sigmoid sinus diverticulum has been considered the most common cause of pulsatile tinnitus; the mechanism underlying sigmoid sinus diverticulum formation is unclear. To the best of our knowledge, no previous studies have assessed whether the formation of sigmoid sinus diverticulum is related to compression of the internal jugular vein by the styloid process.

Objective: To discuss the relationship between the styloid process and the formation of sigmoid sinus diverticulum.

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Objective: We evaluated microwave ablation (MWA) for treatment of idiopathic recurrent anterior epistaxis (RAE) in children, in terms of technical feasibility, efficacy, and safety.

Study Design: A prospective pilot case series.

Setting: Tertiary university hospital.

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Objective: The objective is to reduce the rates of misdiagnosis and inappropriate treatment of laryngeal tuberculosis (LTB).

Study Design: Retrospective case series.

Materials And Methods: Medical records of 3 histopathology-confirmed cases at a tertiary medical center from 2000 to 2018.

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Introduction: Recurrent epistaxis is commonly encountered in the rhinology outpatient clinic. Under endoscopic guidance, both bipolar cautery and monopolar forceps (combined with suction) have been employed to control the bleeding. However, the use of monopolar forceps requires the placement of grounding pads.

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Objective: To compare the outcomes of adult patients with recurrent epistaxis treated intraoperatively with either bipolar electrocautery or microwave ablation (MWA).

Study Design: Prospective randomized control study.

Materials And Methods: One hundred ten patients with idiopathic recurrent epistaxis who met the inclusion criteria were randomly assigned into MWA group and bipolar electrocautery group.

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Some studies have shown that topical application of epidermal growth factor (EGF) accelerates healing in traumatic tympanic membrane perforations (TMPs), however, the optimal dose and starting time of application have not been established. To determine the optimal dose and starting time of application of EGF for the regeneration of TMPs. Patients with traumatic TMPs were first randomly assigned to low-dose EGF, high-dose EGF, and spontaneous healing groups.

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Objective: The objective of this study was to compare the re-bleeding of idiopathic recurrent epistaxis with no definite bleeding site treated with either prophylactic microwave ablation (MWA) or continuous observation.

Study Design: Case series with chart review.

Subjects And Methods: 61 patients with idiopathic recurrent epistaxis but no definite bleeding sites in the first operation were assigned to prophylactic MWA group (n = 39) and continuous observation group (n = 22).

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Objective: To compare the outcomes of adolescent patients with recurrent anterior epistaxis (RAE) treated with either silver nitrate cauterization or microwave ablation (MWA).

Study Design: and methods: In this prospective, randomized study, one hundred 13-18-year-old adolescents with RAE were assigned to two groups: the MWA group (n = 50) or the silver nitrate cauterization group (n = 50). Both groups were followed up for 12 months.

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Background: Arterial epistaxis is commonly seen in the rhinology clinic and can have a significant impact on quality of life. Previous studies have explored various therapies to address epistaxis.

Methods: Patients were treated in the outpatient clinic or operating room by microwave ablation (MWA) with a 2450-MHz cooled-shaft antenna to treat an epistaxis bleeding point.

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Article Synopsis
  • The study aimed to compare the effects of epidermal growth factor (EGF) treatment versus observation on healing human tympanic membrane perforations (TMP).
  • It involved 44 patients, with the EGF group showing a much higher closure rate (96.2%) and faster healing time (mean 9.1 days) compared to the observation group (61.1% closure and mean 20.6 days).
  • The research concluded that EGF treatment significantly enhances TMP healing without the need for invasive procedures, making it a recommended option before undergoing surgery.
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Article Synopsis
  • - The study compared the effectiveness and costs of four treatments for large tympanic membrane perforations (TMPs): ofloxacin drops (OFLX), gelatin sponge patches, spontaneous healing, and endoscopic myringoplasty, involving 100 patients.
  • - Results showed that OFLX had the highest closure rate (95.7%) and shortest average closure time (about 13.7 days), while endoscopic myringoplasty was the most expensive option with significant costs of $715.90.
  • - Although both gelatin sponge and myringoplasty improved closure times compared to spontaneous healing, they didn't show better closure rates, and gelatin sponge treatments had higher costs without significant benefits over OFLX or spontaneous healing.
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Objective: The use of epidermal growth factor (EGF) to achieve closure of human traumatic tympanic membrane perforations (TMPs) was recently reported. However, pretreatment factors affecting healing outcomes have seldom been discussed. This study was performed to evaluate pretreatment factors contributing to the success or failure of TMP healing using EGF.

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Objective: To compare the outcomes of epidermal growth factor (EGF) and gelatin sponge patch treatments for traumatic tympanic membrane perforations.

Study Design: Prospective, randomized, controlled.

Setting: University-affiliated teaching hospital.

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Objective: This study investigated the influence of the degree of bleeding from the remnant eardrum on the spontaneous healing of human traumatic tympanic membrane perforations (TMPs).

Study Design: A case series with chart review.

Setting: A tertiary university hospital.

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