TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology.

Cancer is a complex disease composing systemic alterations in multiple scales. In this study, we develop the Tumor Multi-Omics pre-trained Network (TMO-Net) that integrates multi-omics pan-cancer datasets for model pre-training, facilitating cross-omics interactions and enabling joint representation learning and incomplete omics inference. This model enhances multi-omics sample representation and empowers various downstream oncology tasks with incomplete multi-omics datasets.

Freeform wide-angle camera lens enabling mitigable distortion.

Allowing natural scenes as well as maximizing field of view (FoV) can benefit from the minimization of distortion for the wide-angle camera. The wide-angle camera utilizing freeform surfaces for mitigating distortions, either barrel distortion or pincushion distortion, is therefore of interest. In this paper, the designs of using all-aspherical surfaces and aspherical surfaces combined with freeform surfaces are investigated.

Geometrical-based quasi-aspheric surface description and design method for miniature, low-distortion, wide-angle camera lens.

In addition to utilizing traditional aspheric surfaces, complicated geometric curves for meeting stringent design requirements can also be adopted in optical systems. In this paper, we investigate two geometric shape modeling schemes, namely, pedal and cosine curves, which allow for representation of an S-shaped profile for the optical design of a camera lens. To obtain a powerful tool for representing a quasi-aspheric surface (QAS) to resemble the designed form surface, we linearly combine the pedal/cosine function with a base conic section.

Addressable spatial light modulators for eye-tracking autostereoscopic three-dimensional display using a scanning laser.

A scanning laser-based back light three-dimensional (3D) display capable of rendering full-resolution, low crosstalk, and vivid 3D depth perception has been developed by incorporating time-sequential multiplexing and eye-tracking technologies. This system includes three main subsystems: a scanning laser module, a relay transfer unit created by combining multiple transmissive-type electrically addressed ferroelectric liquid crystal spatial light modulators (FLC-SLMs), and a dual-directional transmission screen (DDTS) unit that can produce different angular magnification factors in both the tangential and sagittal planes. The light beam is directed by the DDTS after transmission through FLC-SLMs, and left and right eye viewing zones are produced sequentially in accordance with the locations of clear apertures in the FLC-SLM that are controlled based on data from the eye-tracking system.

Multi-element direct design using a freeform surface for a compact illumination system.

An iterative optimization algorithm is introduced to address the surface iterative errors as well as source extension issues in a freeform illumination system for producing satisfactory illumination distribution. A unique two-parameter coordinate system is utilized to represent the emitted ray directions. Then, the direction vector for the incident rays, which propagate through several surfaces, is obtained using ray-tracing techniques.

Subpixel area-based evaluation for crosstalk suppression in quasi-three-dimensional displays.

A subpixel area-based evaluation method for an improved slanted lenticular film that minimizes the crosstalk in a quasi-three-dimensional (Q3D) display is proposed in this paper. To identify an optimal slant angle of the film, a subpixel area-based measurement is derived to evaluate the crosstalk among viewing regions of the intended subpixel and adjacent unintended subpixel by taking the real subpixel shape and black matrix into consideration. The subpixel mapping, which corresponds to the optimal slant angle of the film, can then be determined.

Large-aperture transparent beam steering screen based on LCMPA.

A large aperture transmissive step-steering screen composed of a liquid crystal microprism array (LCMPA) deflector and a 90° twisted nematic liquid crystal (TN LC) polarization modulator is developed. The designed 3 in. (7.

Directional view method for a time-sequential autostereoscopic display with full resolution.

A time-sequential autostereoscopic three-dimensional (3D) display using a set of cylindrical optical elements (COEs) as the backlight steering is proposed. The operation principle of the system and its detailed design are described. In our system, the COEs control the direction of the backlight for the proposed system of the user's right and left views.

General construction method for a rotationally symmetric ultrashort distance catadioptric projector.

In this work, the off-axis imaging of a fan of rays with a rotationally symmetric mirror is studied, based on which a general construction method is proposed for the design of a rotationally symmetric ultrashort distance catadioptric projector. With the proposed method, the intermediate images at arbitrary planes of incidence can be obtained, and thus the designer has the freedom to choose suitable intermediate images to simplify the aberration correction of the catadioptric starting point. To prove the effectiveness of the proposed method, the construction process of a convex-type ultrashort distance catadioptric projector is presented.

Field curvature correction method for ultrashort throw ratio projection optics design using an odd polynomial mirror surface.

This paper presents a field curvature correction method of designing an ultrashort throw ratio (TR) projection lens for an imaging system. The projection lens is composed of several refractive optical elements and an odd polynomial mirror surface. A curved image is formed in a direction away from the odd polynomial mirror surface by the refractive optical elements from the image formed on the digital micromirror device (DMD) panel, and the curved image formed is its virtual image.