In vitro assessment of cytotoxicity of spent fluid catalytic cracking refinery catalysts on cell lines and identification of critical toxic metals.

The Purpose of the present study was to quantify the responses of ten cell lines (HeLa, HepG2, HEK293, MDA-MB-231, A498, A549, A357, 3 T3, BALB-C3 T3, and NIH-3 T3) to spent fluid catalytic cracking catalysts (SFCCCs) from different petroleum refineries, and relate these responses to metal concentrations of SFCCC leachates (SFCCCLs). Cytotoxicity of SFCCCs were significantly different depending on cell lines. A357 and 3 T3 cell were the most sensitive, and A498 and HeLa cells were the least sensitive.

Assessment of the relationship between telomere length and atherosclerosis: A Mendelian randomization study.

To evaluate the causal relationship between genetically determined telomere length (TL) and atherosclerosis (AS). We performed a 2-sample Mendelian randomization (MR) study to assess the potential causal relationship between TL and AS (coronary AS, cerebral AS, peripheral atherosclerosis (PAD), and AS, excluding cerebral, coronary, and PAD). The TL phenotype contained 472,174 participants, and the 4 subtypes of AS had 361,194, 218,792, 168,832, and 213,140 participants, all of European ancestries.

Exploring the mechanism of Erchen decoction in the treatment of atherosclerosis based on network pharmacology and molecular docking.

Background: Atherosclerosis (AS) is the cause of most cardiovascular diseases and imposes a huge economic burden on society. Erchen decoction (ECD) is an effective formula for treating AS, but its therapeutic mechanism remains unclear. This study will explore the mechanism of ECD mechanism for treating AS using network pharmacology and molecular docking.

Combined SBAS-InSAR and PSO-RF Algorithm for Evaluating the Susceptibility Prediction of Landslide in Complex Mountainous Area: A Case Study of Ludian County, China.

In complex mountainous areas where earthquakes are frequent, landslide hazards pose a significant threat to human life and property due to their high degree of concealment, complex development mechanism, and abrupt nature. In view of the problems of the existing landslide hazard susceptibility evaluation model, such as poor effectiveness and inaccuracy of landslide hazard data and the need for experts to participate in the calculation of a large number of evaluation factor weight classification statistics. In this paper, a combined SBAS-InSAR (Small Baseline Subsets-Interferometric Synthetic Aperture Radar) and PSO-RF (Particle Swarm Optimization-Random Forest) algorithm was proposed to evaluate the susceptibility of landslide hazards in complex mountainous regions characterized by frequent earthquakes, deep river valleys, and large terrain height differences.

Perfect pair, scopes unite - laparoscopic-assisted transumbilical gastroscopy for gallbladder-preserving polypectomy: A case report.

Background: Gallbladder polyps are one indication for cholecystectomy, but this procedure carries some disadvantages, including the potential for severe injury and high risk of post-operative complications. Laparoscopy combined with endoscopic surgery is a minimally invasive treatment option. We herein report a young patient with a gallbladder polyp who was successfully discharged from the hospital after laparoscopic-assisted endoscopy.

Radiolabeling and Preliminary Evaluation of Tc-Labeled DNA Cube Nanoparticles as Potential Tracers for SPECT Imaging.

Purpose: DNA nanostructures, with the advantages of structural designability and spatial addressability, have shown a great potential in the field of drug delivery and bio-medicine. Herein, we aimed to prepare technetium-99m radiolabeled DNA cube nanoparticles (Tc-DCN) and expect to build a DCN-based drug carrier and nuclear medicine imaging platform.

Methods: DCN could be readily assembled with 6 designed DNA oligonucleotides at an equal mole ratio in a single annealing procedure.

China county-based demographics, clinical characteristics, treatment patterns, and health resource consumption analysis for diabetes.

Background: The diagnosis and treatment of diabetes depends on reasonable chronic disease management. Compared with urban areas, county areas are high-risk areas for chronic disease patients, due to the low awareness of chronic disease, poor treatment compliance with chronic disease, low drug persistence, and low cure rate. Therefore, more attention should be paid to chronic disease management in county areas.

AIB1 predicts tumor response to definitive chemoradiotherapy and prognosis in cervical squamous cell carcinoma.

Amplified in breast cancer 1 (AIB1) gene, has been reported to be associated with biological malignancy in several cancers. However, the molecular status of the AIB1 gene in cervical cancer and the clinicopathological/prognostic significance of AIB1 expression in chemoradiotherapy (CRT) sensitivity have not been determined. In our present study, we found that the high expression of AIB1 was frequent detected in specimens of cervical cancer patients, and this was significantly correlated with CRT response ( = 0.

The Association Between MGMT Promoter Methylation and Patients with Gastric Cancer: A Meta-Analysis.

Aims: Several previous studies have suggested that MGMT promoter methylation is significantly associated with gastric cancer, but the results were not consistent. Hence, we conducted a systematic meta-analysis to explore the potential correlation of MGMT promoter methylation with gastric cancer and its clinicopathologic characteristics.

Materials And Methods: Searches of PubMed, EMBASE, Web of Science, Cochrane Library, and Chinese National Knowledge Infrastructure (CNKI) literature databases were conducted to identify relevant studies published in English or Chinese before July 1, 2016.

[Emissions of greenhouse gas and ammonia from the full process of sewage sludge composting and land application of compost].

There is a great uncertainty of greenhouse gas (GHG) reduction and nitrogen conservation from the full process of sludge composting and land application of compost in China due to the lack of emission data of GHG such as N2O and CH4 and ammonia (NH3). The purpose of this study is to get emission characteristics of GHGs and NH3 from the full process with on-site observation. Results showed that the total GHG emission factor from full process of the turning windrow (TW) system (eCO2/dry sludge, 196.

Dynamic observation of 18F-FDG uptake after oral administration in a healthy subject.

PET with (18)F-FDG is a widely used imaging modality in cancer patients. Traditionally, (18)F-FDG is administrated intravenously. However, patients with difficult venous access are not rare in clinical practice.