Well-defined alginate oligosaccharides ameliorate joint pain and inflammation in a mouse model of gouty arthritis.

Gouty arthritis causes severe pain and inflammation. Alginate oligosaccharides (AOSs) are natural products derived from alginate and have anti-inflammatory properties. We explored the potential effects of AOSs with different degrees of polymerization (Dp) on gouty arthritis and associated mechanisms.

Development and Validation of a Nomogram for Renal Survival Prediction in Patients with Autosomal Dominant Polycystic Kidney Disease.

Introduction: Due to the wide variation in the prognosis of autosomal dominant polycystic kidney disease (ADPKD), prediction of risk of renal survival in ADPKD patients is a tough challenge. We aimed to establish a nomogram for the prediction of renal survival in ADPKD patients.

Methods: We conducted a retrospective observational cohort study in 263 patients with ADPKD.

[Optimization of Stabilizing Agent of Camptothecin Extraction from Nothapodytes pittosporoides Roots].

Objective: To optimize the stabilizing agent of camptothecin extraction from Nothapodytes pittosporoides roots.

Methods: The single factor experiment had been conducted to study the impact on the yield of camptothecin with different kinds of stabilizer, stabilizer concentration and temperature.

Results: The results showed that with 0.