Publications by authors named "Zhenchao Zhang"

Background: Trichomonas vaginalis (T. vaginalis) is a common sexually transmitted parasite that colonizes the human urogenital tract. Programmed and precise detection of T.

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Toxoplasma gondii, a pervasive parasite responsible for toxoplasmosis, poses significant health risks to humans and animals. In this study, we investigated the immunogenicity and protective efficacy of the recombinant T. gondii DDX39 protein formulated with ISA201 adjuvant (rTgDDX39) as a candidate vaccine against toxoplasmosis.

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Yellow leaf mutations have been widely used to study the chloroplast structures, the pigment synthesis, the photosynthesis mechanisms and the chlorophyll biosynthesis pathways across various species. For this study, a spontaneous mutant with the yellow leaf color named 96-140YBM was employed to explore the primary genetic elements that lead to the variations in the leaf color of hot peppers. To identify the pathways and genes associated with yellow leaf phenotypes, we applied sequencing-based Bulked Segregant Analysis (BSA-Seq) combined with BSR-Seq.

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is a ubiquitous protozoon in the intestinal tract of human and many animals. Microscopic examination is the main method of clinical diagnosis for , which is prone to false negative. A simple and rapid diagnosis of infection is an important step to prevent and control blastocystosis.

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This study takes Shanghai's restaurants as a case study of urban soft infrastructure, employing big data sets from third-party website platforms for multi-source data fusion, to deeply analyze the impact of urban land expansion and population dynamics on the availability, affordability, acceptability, and accessibility of restaurants. The case study reveals that, despite the Shanghai municipal authorities' focus on mitigating overcrowding in the central urban areas, soft infrastructure such as restaurants in new urban districts remains at a relative disadvantage. The decentralization of soft infrastructure to peripheral urban areas has not met policy expectations, presenting a spatial imbalance characterized by greater provision in the main urban areas than in new urban districts, and higher in Puxi than in Pudong.

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Cellulose II nanocrystals (CNC II) possess a higher thermal stability and improved emulsifying capability than cellulose I nanocrystals (CNC I) owing to the higher density of their hydrogen bonds and more larger surface areas. Therefore, CNC II exhibit substantial advantages for value-added nanocomposite materials. Current CNC II preparation methods are mainly based on a two-pot reaction involving acid hydrolysis and crystal transformation.

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Magnetic microhelix motors are widely employed in various applications such as cargo transportation, drug delivery, toxic substance declogging, and cell manipulation, due to their unique adaptive magnetic manipulation capabilities. In this work, high-precision stereoscopic additive manufacturing techniques were used to produce customized microhelices with varying structural parameters, including different pitch numbers (2-4 pitches), sizes (0.1-0.

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Background: Trichomonas vaginalis is a protozoan parasite, widely recognized as the most prevalent non-viral sexually transmitted infection (STI) globally. This infection is linked to various complications, including pelvic inflammatory disease, adverse pregnancy outcomes, and an increased risk of acquiring HIV. Current molecular detection methods for T.

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sp. is a prevalent protistan parasite found globally in the gastrointestinal tract of humans and various animals. This review aims to elucidate the advancements in research on axenic isolation techniques for sp.

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Background: Identification of emerging molecular biomarkers on circulating tumor cells (CTCs) represents an attractive feature of liquid biopsy that facilitates precision and tailored medicine in the management of metastatic castration-resistant prostate cancer (mCRPC). Prostein is an androgen-regulated transmembrane protein with high prostate specificity. Prostein-positive circulating tumor cell (CTC) was recently suggested to have diagnostic potential; however, no study has been conducted to evaluate its prognostic value in mCRPC.

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Understanding the determinants of host and tissue tropisms among parasites of veterinary and medical importance has long posed a substantial challenge. Among the seven species of known to parasitize the chicken intestine, a wide variation in tissue tropisms has been observed. Prior research suggested that microneme protein (MIC) composed of microneme adhesive repeat (MAR) domain responsible for initial host cell recognition and attachment likely dictated the tissue tropism of parasites.

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Nearshore water depth plays a crucial role in scientific research, navigation management, coastal zone protection, and coastal disaster mitigation. This study aims to address the challenge of insufficient feature extraction from remote sensing data in nearshore water depth inversion. To achieve this, a convolutional neural network with spatial location integration (CNN-SLI) is proposed.

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Trichomonas vaginalis (T. vaginalis) is a widespread and important sexually transmitted pathogen. Adherence to the surface of the host cell is the precondition forthis parasite's parasitism and pathogenicity.

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Background: Trichomonas vaginalis is a widespread and important sexually transmitted pathogen. Adherence to the surface of the host cell is the precondition for the parasitism and pathogenicity of this parasite. Trichomonas vaginalis adhesion protein 33 (TvAP33) plays a key role in the process of adhesion, but how this protein mediates the adhesion and pathogenicity of T.

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(TV) may have an impact on other reproductive tract infections. Studies on the connection between the infection of TV and human papillomavirus (HPV) have been inconsistent. We performed a systematic review of the relevant articles through keywords that satisfy the criteria and filtered the articles according to the inclusion and exclusion criteria.

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Livestock grazing, as a primary utilization practice for grasslands, plays a crucial role in carbon cycling process and its budget. Whether the impacts of different grazing intensities on carbon sequestration vary with precipitation over a broad geographic scales across China's grasslands remains unclear. In the context of striving for carbon neutrality, we carried out a meta-analysis based on 156 peer-reviewed journal articles to synthesize the general impacts of different grazing intensities on carbon sequestration with different precipitations.

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Article Synopsis
  • The study explored the prevalence of a specific pathogen causing trichomoniasis among men in Xinxiang, collecting 634 clinical samples from semen, prostate fluid, and urine over a 14-month period.
  • Out of these samples, 32 tested positive for the pathogen, leading to detection rates of 7.87% in semen, 4.65% in prostate fluid, and 2.97% in urine.
  • Genetic analysis identified the strains as genotype E, showing high homology with a previously published strain, highlighting the importance of these genetic markers in understanding trichomoniasis in men, though further research is needed on genotype-pathogenicity links.
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Toxoplasma gondii, a highly prevalent apicomplexan pathogen, can cause serious or even fatal toxoplasmosis in both animals and humans. Immunoprophylaxis is considered a promising strategy for controlling this disease. Calreticulin (CRT) is known as a pleiotropic protein, which is critical for calcium storage and phagocytosis of apoptotic cells.

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Background: Trichomonas vaginalis (T. vaginalis) is a microaerophilic protozoan parasite which is responsible for trichomoniasis, the most common non-viral sexually transmitted infection in the world. The infection greatly damages the reproductive system.

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The immunosuppressive receptor TIGIT plays a vital role in the regulation of the immune system's response to pathogens. However, the expression pattern of this receptor in mouse brains during infection with Toxoplasma gondii cysts is not known. Here, we provide evidence of immunological changes and TIGIT expression in infected mouse brains through flow cytometry and QPCR.

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Urban land-use change simulations without considering the sustainable planning policies, especially in special economic park highly concerned by planners, might lack the reliability and availability. Thus, this study proposes a novel planning support systems integrating the Cellular Automata Markov chain model and Shared Socioeconomic Pathways (CA-Markov-SSPs) for predicting the changing of land use and land cover (LULC) at the local and system level by using a novel machine learning-driven, multi-source spatial data modelling framework. Using multi-source satellite data of coastal special economic zones from 2000 to 2020 as a sample, calibration validation based on the kappa indicates a highest average reliability above 0.

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