Experiments about the removal of supersaturated total dissolved gas from water environment by activated carbon adsorption.

Water environment conditions directly support aquatic life. It is important to maintain a suitable water environment to improve the efficient use of water resources. Supersaturation of total dissolved gas (TDG) in the water will cause fish suffer from gas bubble disease and even mortalities.

Prediction model and application of machine learning for supersaturated total dissolved gas generation in high dam discharge.

Supersaturation of total dissolved gas (TDG) caused by high dam discharge is an ecological risk that cannot be ignored in the operation of hydropower stations. The establishment of an efficient and concise TDG generation prediction model is of great significance to the water ecology and water environment protection of hydropower development reaches. The flow conditions and the process of water-gas mass transfer in discharge and energy dissipation are very complicated and difficult to observe in the field, bringing difficulties to the establishment of prediction model and parameter calibration.

Cu-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of -2,2,2-Trifluoroethylisatin Ketimines Enables the Desymmetrization of -Arylmaleimides: Access to Enantioenriched FC-Containing Octahydropyrrolo[3,4-]pyrroles.

With a Cu(OTf)/chiral ferrocenyl P,N-ligand complex as a catalyst, the enantioselective desymmetrization of -arylmaleimides was successfully realized by taking advantage of the asymmetric 1,3-dipolar cycloaddition reaction of -2,2,2-trifluoroethylisatin ketimines. A series of structurally diverse FC-containing octahydropyrrolo[3,4-]pyrroles, bearing four contiguous carbon stereocenters and one stereogenic chiral C-N axial bond, were obtained with excellent results (≤99% yield, >20:1 dr, and 99% ee).

Cost-effectiveness analysis of vonoprazan versus proton pump inhibitors in the treatment of reflux esophagitis in China.

Background: Proton pump inhibitors (PPIs) have been recommended as standard of care for reflux esophagitis (RE). Vonoprazan (VPZ), a novel potassium-competitive acid blocker (P-CAB), has been approved in China after demonstrating clinical benefit in RE. However, there are not any published literature reported the cost-effectiveness of VPZ compared with PPI in Chinese healthcare setting.

Deepened snow loosens temporal coupling between plant and microbial N utilization and induces ecosystem N losses.

Seasonal differences in plant and microbial nitrogen (N) acquisition are believed to be a major mechanism that maximizes ecosystem N retention. There is also a concern that climate change may interrupt the delicate balance in N allocation between plants and microbes. Yet, convincing experimental evidence is still lacking.

Novel Soy Peptide CBP: Stimulation of Osteoblast Differentiation via TβRI-p38-MAPK-Depending RUNX2 Activation.

DEDEQIPSHPPR, the calcium-binding peptide (CBP) identified in soy yogurt, was proven to be a potential cofactor in osteoporosis prevention in our previous study, but the mechanism was unknown. In this study, the activity of alkaline phosphatase (ALP) and osteocalcin (OCN), the regulation of RUNX2, and the expression of TβRI were investigated to elucidate the underlying mechanism. The results show that CBP upregulated ALP activity and OCN concentration and increased the expression of RUNX2 and the activation of the MAPK signaling pathway.

Self-Supervised Enhancement for Named Entity Disambiguation via Multimodal Graph Convolution.

Named entity disambiguation (NED) finds the specific meaning of an entity mention in a particular context and links it to a target entity. With the emergence of multimedia, the modalities of content on the Internet have become more diverse, which poses difficulties for traditional NED, and the vast amounts of information make it impossible to manually label every kind of ambiguous data to train a practical NED model. In response to this situation, we present MMGraph, which uses multimodal graph convolution to aggregate visual and contextual language information for accurate entity disambiguation for short texts, and a self-supervised simple triplet network (SimTri) that can learn useful representations in multimodal unlabeled data to enhance the effectiveness of NED models.

SSA-Net: Spatial self-attention network for COVID-19 pneumonia infection segmentation with semi-supervised few-shot learning.

Coronavirus disease (COVID-19) broke out at the end of 2019, and has resulted in an ongoing global pandemic. Segmentation of pneumonia infections from chest computed tomography (CT) scans of COVID-19 patients is significant for accurate diagnosis and quantitative analysis. Deep learning-based methods can be developed for automatic segmentation and offer a great potential to strengthen timely quarantine and medical treatment.

Catalytic Mechanism of Oxygen Vacancies in Perovskite Oxides for Lithium-Sulfur Batteries.

Defective materials have been demonstrated to possess adsorptive and catalytic properties in lithium-sulfur (Li-S) batteries, which can effectively solve the problems of lithium polysulfides (LiPSs) shuttle and sluggish conversion kinetics during charging and discharging of Li-S batteries. However, there is still a lack of research on the quantitative relationship between the defect concentration and the adsorptive-catalytic performance of the electrode. In this work, perovskites Sr Ti Mn O (STMn ) (x = 0.

Event-Triggered Adaptive Output-Feedback Control of Switched Stochastic Nonlinear Systems With Actuator Failures: A Modified MDADT Method.

This article investigates the adaptive event-triggered output-feedback control problem for a class of switched stochastic nonlinear systems with actuator faults. In the existing works, the developed results on adaptive control for switched stochastic nonlinear systems are almost based on the average dwell-time method, and how to construct a desired adaptive controller in the frame of the mode-dependent average dwell time (MDADT) remains a control dilemma. By presenting a general adaptive control rule based on the MDADT, this article implements the adaptive output-feedback control for the switched stochastic system under interest.

Organocatalyzed asymmetric dearomative 1,3-dipolar cycloaddition of 2-nitrobenzofurans and N-2,2,2-trifluoroethylisatin ketimines.

A readily available chiral cyclohexanediamine-derived bifunctional tertiary amine-squaramide catalyst is more effective for the asymmetric dearomative 1,3-dipolar cycloaddition of 2-nitrobenzofurans and N-2,2,2-trifluoroethylisatin ketimines. A range of structurally diverse spiro-fused polyheterocyclic compounds containing oxindole, pyrrolidine, and hydrobenzofuran motifs were smoothly obtained in excellent results (up to 99% yield, >20:1 dr in all cases and up to 99% ee). This method features high efficiency, mild reaction conditions, exquisite asymmetric induction, wide functional group tolerance, great potential for scale-up synthesis, and attractive product diversification.

Insights into the Interactions Between Root Phenotypic Traits and the Rhizosphere Bacterial Community.

The root phenotypic traits have been considered as important factors in shaping the rhizosphere microbiome and regulating plant growth. However, the relationships between root phenotypic traits and the rhizosphere bacterial community remain unclear. We investigated two fields with different developing tobacco roots by a long-term positioning test in Hengshi.

Access to 4-Trifluoromethyl Quinolines via Cu-Catalyzed Annulation Reaction of Ketone Oxime Acetates with -Trifluoroacetyl Anilines under Redox-Neutral Conditions.

An efficient Cu-catalyzed annulation reaction of ketone oxime acetates with -trifluoroacetyl anilines has been disclosed. With the developed protocol, a series of 4-trifluoromethyl quinolines were obtained in good to excellent yields (58-99%) under redox-neutral conditions. The protocol also could be extended to ferrocene-based ketone oxime acetates for the construction of ferrocene-substituted fluorine-containing quinolines.

Pre-existing hypertension is associated with poor progression-free survival in newly diagnosed multiple myeloma patients.

Approximately 31% of patients diagnosed with multiple myeloma (MM) have pre-existing hypertension, but its effects on patient survival have not been investigated. We collected data from 228 newly diagnosed patients with MM and found that 71 (31.1%) had pre-existing hypertension.

Dearomatization of 3-Nitroindoles Enabled Using Palladium-Catalyzed Decarboxylative [4 + 2] Cycloaddition of 2-Alkylidenetrimethylene Carbonates.

A dearomatization process of 3-nitroindoles enabled using palladium-catalyzed decarboxylative [4 + 2] cycloaddition of either 2-alkylidenetrimethylene carbonates or 2-(hydroxymethyl)-3-arylallyl carbonates has been developed, affording a wide range of indoline-fused tetrahydropyrans in good yields with excellent diastereoselectivities. This reaction features a wide substrate scope and mild conditions and represents the first example of the application of π-allyl palladium 1,4-[,]-dipole species for the dearomative cycloaddition of electron-deficient heteroarenes.

Preparative isolation of maltol glycoside from and its anti-inflammatory activity .

is a traditional Chinese medicine that is commonly utilized as a treatment for inflammation, pain, and immunological conditions. In this study, an anti-inflammatory maltol glycoside derived from was isolated for the first time medium and high-pressure liquid chromatography, and at the same time, the anti-inflammatory activity of this maltol glycoside was preliminarily explored. Initially, crude samples of were preprocessed MCI GEL® CHP20P and Spherical C18 medium-pressure chromatography, under the guidance of evaluation of anti-inflammatory activity.

Promoting and inhibiting: Corporate charitable donations and innovation investment under different motivation orientations--Evidence from Chinese listed companies.

Corporate charitable donations under different motivations will have different effects on innovation investment through different action paths, which provides a new perspective to solve the inconsistency of existing research results. Based on the resource-dependent and principal-agent theories, this paper compares and discusses the relationship between charitable donations and innovation investment under different motivations. Using 2008 ~2019 relevant data of listed companies as research samples, a mixed regression model is established for the hypothesis test, and further examines the state-ownership of its moderating role.

Health-related quality of life among Chinese patients with Crohn's disease: a cross-sectional survey using the EQ-5D-5L.

Background: Crohn's disease (CD) is a chronic disease that may have an adverse impact on health-related quality of life (HRQoL). This study aimed to describe the HRQoL of CD patients and assess correlating factors using the EQ-5D-5L in China.

Methods: We recruited CD patients at Shanghai Renji Hospital from October 2018 to May 2019.

A Three-Year Plant Study of Salt-Tolerant Transgenic Maize Showed No Effects on Soil Enzyme Activity and Nematode Community.

The environmental effects of genetically modified crops are now a global concern. It is important to monitor the potential environmental impact of transgenic corn after commercial release. In rhizosphere soil, plant roots interact with soil enzymes and microfauna, which can be affected by the transgenes of genetically modified crops.

Genome-Wide Profiling of Alternative Splicing and Gene Fusion during Rice Black-Streaked Dwarf Virus Stress in Maize ( L.).

Rice black-streaked dwarf virus (RBSDV) causes maize rough dwarf disease (MRDD), which is a viral disease that significantly affects maize yields worldwide. Plants tolerate stress through transcriptional reprogramming at the alternative splicing (AS), transcriptional, and fusion gene (FG) levels. However, it is unclear whether and how AS and FG interfere with transcriptional reprogramming in MRDD.

Ultra-Robust and Extensible Fibrous Mechanical Sensors for Wearable Smart Healthcare.

Fibrous material with high strength and large stretchability is an essential component of high-performance wearable electronic devices. Wearable electronic systems require a material that is strong to ensure durability and stability, and a wide range of strain to expand their applications. However, it is still challenging to manufacture fibrous materials with simultaneously high mechanical strength and the tensile property.

Analysis of the role and mechanism of EGCG in septic cardiomyopathy based on network pharmacology.

Background: Septic cardiomyopathy (SC) is a common complication of sepsis that leads to an increase in mortality. The pathogenesis of septic cardiomyopathy is unclear, and there is currently no effective treatment. EGCG (epigallocatechin gallate) is a polyphenol that has anti-inflammatory, antiapoptotic, and antioxidative stress effects.

The Temporal and Spatial Changes of Health Inequality in Rural China.

This article estimates the temporal and spatial changes of health inequality in rural China from 2010 to 2018. Based on a panel database of 29,616 rural residents, the Health Utility Index (HUI) and a spatial econometric model are used for analysis. The results show that, on the temporal dimension, the health inequality of rural China first expands and then deflates.

Inverse Electron-Demand Aza-Diels-Alder Reaction of α,β-Unsaturated Thioesters with In Situ-Generated 1,2-Diaza-1,3-dienes for the Synthesis of 1,3,4-Thiadiazines.

A highly regioselective inverse electron-demand aza-Diels-Alder reaction of -unsaturated thioesters with 1,2-diaza-1,3-dienes generated in situ from α-halogeno hydrazones was developed. With α,β-unsaturated thioesters as C═S dienophiles, the developed protocol enables the formation of diverse 3,6-dihydro-2-1,3,4-thiadiazine derivatives in excellent yields. In the presence of lithium aluminum hydride, 3,6-dihydro-2-1,3,4-thiadiazine derivatives could be further transformed into 5,6-dihydro-4-1,3,4-thiadiazines in good yields.