Publications by authors named "Zhen-xi Qi"
Article Synopsis
- Sclerosis rim, often found around necrotic areas in the femoral head, has not been sufficiently studied for its biomechanical role in bone health.
- This research explores how necrosis affects bone remodeling and how the sclerosis rim may help delay the collapse of the femoral head.
- Findings suggest that the sclerosis rim adapts to changes in the femoral head's stiffness, effectively reducing maximum stress in the bone when the necrotic area is small, but losing effectiveness with larger lesions.
Objective: To observe the effect of Hydroxy Safflower Yellow A (HSYA) on the expression of osteogenic markers, such as alkaline phosphatase, Cbf(alpha)l and type I collagen, and explore the mechanism of HSYA in the prevention and treatment of glucocorticoid-induced ischemic necrosis of femoral head.
Methods: Fifteen healthy and adult New Zealand white rabbits were collected and weighted 0.9 to 1.
[Influence of ground beetle on steroid-induced BMSCs osteogenic differentiation].
Zhongguo Gu Shang
December 2010
Objective: To investigate the pathogenesis of steroid-induced avascular necrosis of femoral head and the control mechanisms of Ground Beetle.
Methods: The bone marrow-derived mesenchymal stem cells were cultured in vitro. The BMSCs in the 3rd generation were randomly divided into blank group, model group and Chinese medicine low, medium and high dose group.
Objective: To establish rat models of Steroid-avascular necrosis of femoral head, observe the effects of activating blood circulation of chinese herbal medicine on genetic expression of transforming growth factor-beta1 (TGF-beta1). To interpret the mechanism of the effect on Steroid-avascular necrosis of femoral head by activating blood circulation,and offer a effective method to clinical.
Methods: Cleaner-40 SD rats,half males and half females, weight (200 +/- 20) g, were randomly divided into 2 groups: 4 rats were in common group and 36 rats were in medel group.
Objective: To probe into the mechanism of Chinese drugs for promoting blood circulation and eliminating blood stasis in the prevention and treatment of glucocorticoid-induced ischemic necrosis of femoral head.
Methods: Thirty New Zealand adult white rabbits were randomly divided into a normal control group (n=5) and a model group (n=25). Hydroxyprednisone acetate was intramuscularly administered to the rabbits in the model group in a dosage of 7.