Layered Co-O Cluster Applied to Photocatalytic CO Reduction.

In the field of recycling CO, the photocatalytic CO reduction reaction (CORR) is a typical example, and researchers have designed a variety of photocatalysts to improve the conversion rate of CO over the years. In this paper, two metal-oxygen clusters are designed and formulated as [CoZn(OH)(SO)]·4HO () and [NiZn(OH)(SO)]·4HO (). As for compound , the main structure is composed of {CoO} octahedra connected by edge-sharing to form a two-dimensional layer, on which {ZnO} and {SO} tetrahedra are supported.

Residues and dietary risk assessment of fluazinam in root mustard after field experiments.

The residue levels of fluazinam in root mustard were investigated by using a quick, easy, cheap, effective, rugged, and safe (QuEChERS) technique with ultra-performance liquid chromatography tandem mass spectrometry. Samples of leaf and root mustard were analyzed. The recoveries of fluazinam were 85.

[Characteristics of water requirement of table grape in the growing season].

To quantitatively assess the satisfaction degree of precipitation on water requirement of table grape in the main producing areas in China, we analyzed the temporal and spatial variations of precipitation, water requirement and water deficit in different growth stages of table grape based on the 1981-2016 daily meteorological data from 429 meteorological stations in the study region (Jinlin and Liaoning of Northeast China; Shanxi and Hebei of North China; Xinjiang, Gansu, Ningxia and Shaanxi of Northwest China; Sichuan, Guizhou and Yunnan of Southwest China; Jiangsu, Shandong, Zhejiang, Anhui, Fujian, Henan, Hubei, Hunan and Guangxi of Southeast China). Results showed that precipitation in each growth stage showed an increasing trend from north to south and from west to east in the study period. The precipitation in germination-flowering stage was the lowest and showed a decreasing trend.

[Spatial-temporal characteristics of agricultural climate resources and sterile-type chilling injury in rice growing season in three provinces of Northeast China].

Based on daily meteorological data and agro-meteorological data in three provinces of Northeast China during 1981-2017, combined with chilling injury indices, we analyzed the spatial-temporal distribution characteristics of solar, heat, precipitation resources and sterile-type chilling injury in rice growing season, especially in the booting and flowering stages. In 1981-2017, agriculture climatic resources in rice growing season showed a warming, drying and darkening trend. Accumulated temperature (≥10 ℃) and sunshine hours increased with a rate of 73.

The evaluation of sleep disturbances for Chinese frontline medical workers under the outbreak of COVID-19.

Objective: To evaluate sleep disturbances of Chinese frontline medical workers (FMW) under the outbreak of coronavirus disease 2019 (COVID-19), and make a comparison with non-FMW.

Methods: The medical workers from multiple hospitals in Hubei Province, China, volunteered to participate in this cross-sectional study. An online questionnaire, including Pittsburgh Sleep Quality Index (PSQI), Athens Insomnia Scale (AIS) and Visual Analogue Scale (VAS), was used to evaluate sleep disturbances and mental status.

Intracellular Restructured Reduced Glutathione-Responsive Peptide Nanofibers for Synergetic Tumor Chemotherapy.

Self-assembled peptide nanofibers have been widely studied in cancer nanotherapeutics with their excellent biocompatibility and low toxicity of degradation products, showing the significant potential in inhibiting tumor progression. However, poor solubility prevents direct intravenous administration of nanofibers. Although water-soluble peptide precursors have been formed via the method of phosphorylation for intravenous administration, their opportunities for broad in vivo application are limited by the weak capacity of encapsulating drugs.

AIE/FRET-based versatile PEG-Pep-TPE/DOX nanoparticles for cancer therapy and real-time drug release monitoring.

On account of the biological significance of self-assembling peptides in blocking the cellular mass exchange as well as impeding the formation for actin filaments resulting in program cell death, stimuli-responsive polypeptide nanoparticles have attracted more and more attention. In this work, we successfully fabricated doxorubicin-loaded polyethylene glycol-block-peptide (FFKY)-block-tetraphenylethylene (PEG-Pep-TPE/DOX) nanoparticles, where the aggregation-induced emission luminogens (AIEgen, TPE-CHO) can become a fluorescence resonance energy transfer (FRET) pair with the entrapped antitumor drug DOX to detect the release of drugs dynamically. This is the first successful attempt to detect and quantify the change of FRET signals in A549 cells via three methods to monitor the cellular uptake of nanoprobes and intracellular drug molecule release intuitively.

Doxorubicin derivative loaded acetal-PEG-PCCL micelles for overcoming multidrug resistance in MCF-7/ADR cells.

This study was aimed to develop DOX-TPP loaded acetal-PEG-PCCL micelles to improve the clinical efficacy of drug resistance tumor. Chemotherapy is one of the main treatments for breast cancer but is plagued by multidrug resistance (MDR). DOX-TPP-loaded micelles can enhance the specific concentration of drugs in the tumor and improve the efficacy and overcome MDR.

Stimulus-responsive nanoscale delivery systems triggered by the enzymes in the tumor microenvironment.

The tumor microenvironment is the cellular environment that is also described as the "soil" for supporting tumor growth, proliferation, invasion and metastasis, as well as protecting tumor cells from immunological recognition. Notably, tumor cells can grow much faster than other normal organs and invade surrounding tissues more easily, which results in abnormal expression of enzymes in the tumor microenvironment, including matrix metalloproteinases, cathepsins, phospholipases, oxidoreductases, etc. In opposite, due to the high selectivity and catalytic activity, these enzymes can promote nanoparticles to recognize tumor tissues more accurately, and the more accumulation of drugs at primal tumor sites will enhance therapeutic efficacy with lower systemic toxicity.

Distinguishing Majorana bound states and Andreev bound states with microwave spectra.

Majorana fermions are a fascinating and not yet confirmed quasiparticles in condensed matter physics. Here we propose using microwave spectra to distinguish Majorana bound states (MBSs) from topological trivial Andreev bound states. By numerically calculating the transmission and Zeeman field dependence of the many-body excitation spectrum of a 1D Josephson junction, we find that the two kinds of bound states have distinct responses to variations in the related parameters.

Closure of patent foramen ovale for cryptogenic stroke patients: an updated systematic review and meta-analysis of randomized trials.

Objective: This systematic review and meta-analysis was performed to investigate the efficacy and safety of transcatheter device closure (TDC) plus anti-thrombotic drugs over medical management alone for patients with cryptogenic stroke and patent foramen oval.

Methods: PubMed, Embase and Cochrane Library database were searched for randomized controlled clinical trials (RCTs). The primary endpoint is the composite of stroke and transient ischemic attack.

Comparative chromosomal localization of 45S and 5S rDNAs and implications for genome evolution in Cucumis.

Ribosomal DNAs are useful cytogenetic markers for chromosome analysis. Studies investigating site numbers and distributions of rDNAs have provided important information for elucidating genome organization and chromosomal relationships of many species by fluorescence in situ hybridization. But relevant studies are scarce for species of the genus Cucumis, especially in wild species.

A screen of suitable inducers for germline differentiation of chicken embryonic stem cells.

Differentiation of germ cells from embryonic stem cells in vitro could have great application for treating infertility and provide an excellent model for uncovering molecular mechanisms of germline generation. In this study, we aim to screen the suitable inducers that may prove the efficiency of driving chicken embryonic stem cells (ES cells) toward germ cells. The male ES cells were separeted into different groups: single retinoic acid (RA) treatment, co-cultured with sertoli cell feeder with RA induction, cultured on matrix proteins (fibronectin, laminin and collagen) with RA treatment, cultured on fibronectin with sertoli cell feeder and RA induction, and single bone morphogenetic protein 4 (BMP4) treatment.

Morin exerts neuroprotective actions in Parkinson disease models in vitro and in vivo.

Aim: To investigate the neuroprotective effects of morin on 1-methyl-4-phenylpyridinium ion (MPP(+))-induced apoptosis in neuronal differentiated PC12 cells as well as in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson disease (PD).

Methods: PC12 cells were challenged with MPP(+) in the presence or absence of morin. Cell viability was determined using MTT assay.

Effects of dietary intervention on hyperlipidemia in eight communities of Beijing, China.

Objective: To examine the effect of community-based dietary intervention on hyperlipidemia.

Methods: A total of 180 hyperlipidemia individuals with TG>2.26 mmol x L(-1) (200 mg x dL(-1)) and/or TC>5.