Publications by authors named "Zhen-song Yao"

Background: Facet tropism is defined as the asymmetry between the left and right facet joints relative to the sagittal plane. Published clinical studies have found that facet tropism is associated with cervical disc herniation. However, the relationship between the facet orientation and the side of cervical disc herniation remains controversial.

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  • - The study investigates the risk factors associated with hidden blood loss in patients with osteoporosis who experience vertebral compression fractures and undergo percutaneous vertebral augmentation between October 2018 and December 2019.
  • - A total of 360 patients were analyzed, looking at various factors such as age, surgical methods, bone density, and preoperative blood metrics, to determine their relationship with hidden blood loss.
  • - Key findings reveal that factors like surgical methods, type of operation, duration of disease, and lower preoperative hemoglobin are significantly linked to increased hidden blood loss during these procedures.
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Background: Insufficient cement distribution (ICD) in the fractured area has been advocated to be responsible for unsatisfied pain relief after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCFs). However, little is known about risk factors for the occurrence of ICD.

Objective: The present study aimed to identify independent risk factors of the emergence of ICD.

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Osteoporotic vertebral fracture (OVF) is a worldwide health concern and lacks sufficient basic studies. Suitable animal models should be the foundation for basic study and treatment of OVF. There have been few studies on the development of animal models of osteoporotic vertebral bone defects.

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  • The study aimed to develop a method for detecting spinal tuberculosis (TB) using the ELISPOT assay and investigate the efficacy of the CFP10/ESAT6 fusion protein in diagnosing spinal TB.
  • Data were collected from patients suspected of having spinal TB in two hospitals over 18 months, with a focus on comparing ELISPOT with traditional diagnostic methods.
  • The results indicated that the ELISPOT assay demonstrated higher sensitivity and specificity (82.7% and 87.2%, respectively) compared to conventional tests like the PPD skin test and antibody detection, suggesting it is a reliable supplementary diagnostic tool for spinal TB.
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Background: According to some clinical studies, insufficient cement distribution (ID) in the fractured area and asymmetrical cement distribution around the fractured area were thought to be the reasons for unrelieved pain and recollapse after percutaneous vertebral augmentation (PVA) in the treatment of symptomatic osteoporotic vertebral compression fractures.

Methods: Finite element methods were used to investigate the biomechanical variance among three patterns of cement distribution (ID and sufficient cement distribution in the fractured area and asymmetrical cement distribution around the fractured area including upward [BU] and downward [BD] cement distribution).

Results: Compared with fractured vertebra before PVA, distribution of von Mises stress in the cancellous bone was transferred to be concentrated at the cancellous bone surrounding cement after PVA, whereas it was not changed in the cortical bone.

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