[Retrospection and recent advances in fluid resuscitation during burn shock stage].

To retrospect the development of fluid resuscitation for burn shock and to look to the future. The main achievements in burn care in the past fifty years and existing problems are summarized, and the appropriate regime of fluid resuscitation for burn shock is suggested. Numerous achievements in burn care have been made, including the estimation of burn area, fluid replenishment formula, delayed resuscitation, fluid resuscitation for burn shock complicated by inhalation injury, covert compensatory shock and research on mechanism of burn shock etc.

[Application of carbon fiber dressing on burn wounds].

Objective: To observe the effects of carbon fiber dressing on burn wounds.

Methods: Two hundreds and seventy seven burn patients were randomly divided into treatment group (group T) and control group (group C). The burn wounds were covered with carbon fiber dressing in T group, and with povidone iodine gauze in C group, respectively.

[Effects of zinc supplementation on zinc and calcium levels in serum and tissue in burned rats].

Objective: To explore the effects of zinc supplementation on zinc and calcium levels in serum and tissue in burned rats.

Methods: Eighty SD rats were randomly divided into C group (control group without scald, n = 8), and N, W, H groups (each consisting of 24 rats), in which the rats were exposed to scalding resulting in partial thickness burns covering 15% of the total body surface area on the back, and then they were fed with diets containing zinc 40 microg/g in N and W groups, and 80 microg/g in H group. A cream containing zinc 761.

[The influence of lipopolysaccharide on adipose metabolism in liver during shock stage of scalded rats].

Objective: To investigate the influence of lipopolysaccharide (LPS) on adipose metabolism in liver during shock stage of scalded rats.

Methods: Sixty adult Wistar rats were inflicted with 30% TBSA full thickness scald and were randomly divided into 3 groups: i. e.

[Effect of growth hormone on non-protein respiratory quotient and oxidation rate of protein after burn injury].

Objective: To investigate the changes in non-protein respiratory quotient (NPRQ) and oxidation rate of protein after burn injury, and the effect of growth hormone (GH) administration on metabolism.

Methods: Sixteen male minipigs were subjected to 35% total body surface area (TBSA) full thickness burn, and the burned minipigs were randomly divided into two groups: GH group and control group. NPRQ and oxidation rate of protein were monitored by means of the metabolic cart.

[Changes in uncoupling protein-2, 3 mRNA expression in the scalded rats after escharectomy at different post scalding stages].

Objective: To investigate the expression of uncoupling protein (UCP)-2, 3 mRNA in skeletal muscle of the scalded rats after escharectomy at different post scalding stages.

Methods: One hundred and twenty Wistar rats were employed in the study, in which 8 served as normal control (C) and 112 were subjected to 30% TBSA 3rd degree scalding and then again, divided into 4 groups. The rats in A group were sacrificed on 8th, 24th, 96th, 120th and 168th post scalding hours (PSHs) without escharectomy.

[Effects of escharectomy during burn shock stage on the mRNA expression of IFN-gamma and IL-4 in spleen T lymphocytes in rats after thermal injury].

Objective: To determine the serum level and mRNA expression of type-1/type-2 cytokines of T lymphocytes in spleens of rats after thermal injury and to investigate the effects of escharectomy during burn shock stage on IFN-gamma and IL-4.

Methods: One hundred and sixty male Wistar rats were randomized into four groups. In group A, animals were not subjected to escharectomy.

[Application of digital subtraction angiography and type B ultrasonography in the evaluation of vascular injury in patients with high voltage electrical injury].

Objective: To compare the difference between digital subtraction angiography (DSA) and type B ultrasonography in the evaluation of vascular injury in patients inflicted with high voltage electrical injury.

Methods: Nineteen patients with high voltage electrical injury of upper limbs were enrolled in the study as burn group, and another 12 healthy volunteers as controls. The endovascular membrane, vascular wall thickness, intra-vascular blood flow and endovascular thrombosis formation of ulnar and radial arteries at wound site and in regions 5, 10 and 15 cm proximal to the wounds were examined by DSA and type B ultrasonography and compared with imagings of healthy volunteers as control.

[Effects of the escharectomy during burn shock stage on expression of glucose translator-4 mRNA in skeletal muscle and adipose tissue].

Objective: To investigate the effect of the escharectomy during burn shock stage on expression of glucose translator-4 (GLUT4) mRNA in skeletal muscle and adipose tissue.

Methods: 30% TBSA scalded rats were employed. Escharectomy were conducted at 8 h, 24 h, 168 h after burns respectively.

[The effects of early escharectomy on resting energy expenditure in the severely burned patients].

Objective: To investigate the effect of early escharectomy on resting energy expenditure (REE) in severely burned patients dynamically with the metabolic monitoring and diagnostic system.

Methods: Fifty-six adult male patients with severe burns were divided into early escharectomy (group A, n = 39, escharectomy within 5 PBDs) and non-early escharectomy (group B, n = 17, escharectomy after 5 PBDs) groups. The wounds of full thickness and deep partial thickness burn in the two groups were all excised and covered with allogeneic skin and autologous micro-skin in the first operation.

[Escharectomy during burn shock on Th1/Th2 polarization of helper T lymphocytes in rats after thermal injury].

Objective: To determine the type-1/type-2 cytokine response of helper T lymphocytes after thermal injury, and to investigate the effects of escharectomy during burn shock stage on the polarization of Th cells.

Methods: One hundred and sixty male Wistar rats were randomized into four groups. In group A, animals were subjected to a 30 percent full-thickness thermal injury without escharectomy.

[Effects of escharectomy during shock stage on the plasma lipid and serum free fatty acid levels in scalded rats].

Objective: To investigate the influence of escharectomy during shock stage on plasma lipid and free fatty acid levels in scalded rats.

Methods: Thirty-two adult Wistar rats inflicted with 30% TBSA III degree scalding were employed as the model and were divided into normal control (NC), scalding control (SC) and treatment groups (T), and the latter was further divided into three sub groups according to the time of escharectomy, i.e.

[The application of ultrasonography in the diagnosis of deep electric injury].

Objective: To explore the application of ultrasonography in the diagnosis of deep electric injury.

Methods: HP-IPHX high resolution color and pulse doppler ultrasonography was employed in the study. The hemodynamic indices were determined in the burn wound area and tissues 5 - 15 cm proximal to the wound in 12 patients with deep electric injury.