[Application of membrane induced by antibiotic loaded bone cement in skin grafting for tendon exposed wound healing].

Objective: To evaluate the effects of membrane induced by antibiotic-loaded bone cement in skin grafting for tendon exposed wound healing.

Methods: A total of 10 traumatic patients with tendon exposed wound were admitted to our department between February 2016 and December 2018, including 6 males and 4 females, with a mean age of 34.6 years old (ranged, 19 to 43 years old), and treatment duration ranged from 2 to 6 months.

corrosion resistance of layer-by-layer assembled polyacrylic acid multilayers induced Ca-P coating on magnesium alloy AZ31.

Biodegradable magnesium (Mg)-based alloys have aroused great concern owing to their promising characteristics as temporary implants for orthopedic application. But their undesirably rapid corrosion rate under physiological conditions has limited the actual clinical application. This study reports the use of a novel biomimetic polyelectrolyte multilayer template, based on polyvinylpyrrolidone (PVP) and polyacrylic acid (PAA) via layer-by-layer (LbL) assembly, to improve the corrosion resistance of the alloy.

Visualization of Higher-Order Topological Insulating Phases in Two-Dimensional Dielectric Photonic Crystals.

The studies of topological phases of matter have been developed from condensed matter physics to photonic systems, resulting in fascinating designs of robust photonic devices. Recently, higher-order topological insulators have been investigated as a novel topological phase of matter beyond the conventional bulk-boundary correspondence. Previous studies of higher-order topological insulators have been mainly focused on the topological multipole systems with negative coupling between lattice sites.

Graphene Plasmon-Enhanced IR Biosensing for in Situ Detection of Aqueous-Phase Molecules with an Attenuated Total Reflection Mode.

Graphene plasmon has attracted extensive interest due to the unprecedented electromagnetic confinement, long propagation distance, and tunable plasmonic frequency. Successful applications of graphene plasmon as infrared sensors have been recently demonstrated, yet they are mainly focused on solid/solid and solid/gas interfaces analysis. Herein, we, for the first time, propose a graphene plasmon-enhanced infrared sensor based on attenuated total reflection configuration for in situ analysis of aqueous-phase molecules.

Endoscopic Approach to Remove Intra-extracranial Tumors in Various Skull Base Regions: 10-year Experience of a Single Center.

Background: Some problems have been found in the usually adopted combined approach for the removal of intra-extracranial tumors in skull base. Herein, we described a pure endoscopic transnasal or transoral approach (ETA) for the removal of intra-extracranial tumors in various skull base regions.

Methods: Retrospectively, clinical data, major surgical complications, pre- and postoperative images, and follow-up information of a series of 85 patients with intra-extracranial tumors in various skull base regions who were treated by surgery via ETA in our skull base center during the past 10 years were reviewed and analyzed.

Clinicopathological significance of p16, cyclin D1, Rb and MIB-1 levels in skull base chordoma and chondrosarcoma.

Objective: To investigate the expression of p16, cyclin D1, retinoblastoma tumor suppressor protein (Rb) and MIB-1 in skull base chordoma and chondrosarcoma tissues, and to determine the clinicopathological significance of the above indexes in these diseases.

Methods: A total of 100 skull base chordoma, 30 chondrosarcoma, and 20 normal cartilage tissue samples were analyzed by immunohistochemistry. The expression levels of p16, cyclinD1, Rb and MIB-1 proteins were assessed for potential correlation with the clinicopathological features.

The effects of Cordyceps sinensis phytoestrogen on estrogen deficiency-induced osteoporosis in ovariectomized rats.

Background: Isoflavones are naturally occurring plant chemicals belonging to the "phytoestrogen" class. The aim of the present study was to examine the effects of isoflavones obtained from Cordyceps sinensis (CSIF) on development of estrogen deficiency-induced osteoporosis in ovariectomized rats.

Methods: After the rats were treated orally with CSIF, serum alkaline phosphatase (ALP), tartarate resistant acid phosphatase (TRAP), serum osteocalcin (OC), homocysteine (HCY), C-terminal crosslinked telopeptides of collagen type I (CTX), estradiol and interferonγ (IFN-γ) level were examined.

Distance-determined sensitivity in attenuated total reflection-surface enhanced infrared absorption spectroscopy: aptamer-antigen compared to antibody-antigen.

Distance-dependent signal intensity in immunoassay by attenuated total reflection-surface enhanced infrared absorption spectroscopy is demonstrated by controlling the distance of target proteins away from the enhancement substrate. Based on this optical near-field effect, sensitive detection of protein molecules with a detection limit of 0.6 nM and investigation of the kinetics and thermodynamics of protein-aptamer/antibody interactions can be achieved.

Cordycepin (3'-deoxyadenosine) down-regulates the proinflammatory cytokines in inflammation-induced osteoporosis model.

The effect of cordycepin (3'-deoxyadenosine) on inflammation-induced osteoporosis (IMO) was studied in this paper. After the rats were treated orally with cordycepin (20 mg/kg), serum osteocalcin (OC), homocysteine (HCY), C-terminal cross-linked telopeptides of collagen type I (CTX), maleic dialdehyde (MDA), polymorphonuclear cells (PMN), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α), they were examined by ELISA or immunohistochemistry. The specimens from the liver were also processed for light microscopic examination.

[Early experience of resection of meningiomas in anterior skull base with intra-extracranial extension via a pure endoscopic endonasal approach].

Objective: The early experience of treating anterior skull base meningiomas with intra-extracranial extension via pure endoscopic endonasal approach (EEA) was presented, the safety, feasibility and preliminary treatment outcomes were investigated.

Methods: Eight patients with intra-extradural meningiomas who were admitted from October 2006 to October 2010 were operated on via EEA in one stage in Xuanwu hospital. In this study, the operative technique was described, the degree of resection, complications and the early clinical outcomes were discussed.

[Responses of winter wheat tillers at different positions to low temperature stress at stem elongation stage and their freezing resistance evaluation].

Taking two winter wheat cultivars Ji' nan 17 and Shannong 8355 as test materials, this paper measured the superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities and the malondialdehyde (MDA) and soluble protein contents in the functional leaves and sheaths of the tillers at different positions at stem elongation stage under low temperature stress, and then, the freezing resistance of the tillers was comprehensively evaluated by the methods of principal component analysis and cluster analysis. The results showed that under low temperature stress, the SOD, POD, and CAT activities in the functional leaves and sheaths of each tiller at stem elongation stage increased, but the MDA and soluble protein contents increased or decreased to some extent. By using principal component analysis and cluster analysis, the tillers of each cultivar were grouped into three kinds of freezing resistance type.

Poly(L-lactic acid)/hydroxyapatite/collagen composite coatings on AZ31 magnesium alloy for biomedical application.

Surface modification of biomedical magnesium alloy using composite coating shows an attemptable approach for the development of Mg-based biomaterials with excellent cytocompatibility. Hydroxyapatite/collagen composite was preliminarily fabricated by biomineralization, the bioactive poly(l-lactic acid)/hydroxyapatite/collagen composite coatings were spin coated on AZ31 magnesium alloy using poly(l-lactic acid) solution mixed with hydroxyapatite/collagen particles, and the resultant materials and coatings were characterized in structure and related properties; furthermore, the in vitro degradation behavior of modified magnesium alloy in 1.5-fold Hank's solution was investigated.

[Surgery for jugular foramen schwannomas via a pure endoscopic transoral approach].

Objective: To report a new approach, endoscopic transoral approach for the resection of jugular foramen schwannoma.

Methods: Nine patients with jugular foramen schwannoma (three males and six females, ranging in age from 15 to 61 years old) were treated by direct surgery via a pure endoscopic transoral approach to the jugular foramen. Eight patients complained of hypoglossal nerve palsy with hemiatrophy of the tongue; six cases complained of vagus nerve palsy.

Endoscopic transsphenoidal approach to pituitary adenomas invading the cavernous sinus.

Background: Surgery of pituitary adenomas invading cavernous sinus has always been thought as a challenge due to the complex anatomical structures and high risk of complications. The purpose of this study was to evaluate endoscopic transsphenoidal approach to pituitary adenomas invading cavernous sinus.

Methods: The clinical data of 22 patients who admitted to Xuanwu Hospital with pituitary adenomas invading cavernous sinus were analyzed retrospectively.

[Freeze resistance analysis of different wheat cultivars based on the relationships between physiological indices and grain yield].

A pot experiment with twenty wheat cultivars was conducted to investigate the superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activities and the MDA, soluble protein and soluble sugar contents of functional leaves as well as the grain yield, 1000-grain weight, and grain morphological characters under low temperature stress. Low temperature (-4 degrees C) stress at stem elongation stage resulted in the changes of grain morphology and yield characters. For most of test cultivars, their grain length-width ratio, grain roundness, and sterile spikelets increased, and their grain equivalent diameter, grain area, 1000-grain weight, and grain yield decreased.

[Effects of planting density and spraying PP333 on winter wheat lodging-resistance and grain yield].

Taking two winter wheat varieties Gaocheng 8901 and Yannong 21 with different end-use qualities as test objects, a field experiment was conducted in the experimental farm of Shandong Agricultural University from 2008 to 2010, aimed to study the effects of different planting density and spraying PP333 on the basal stem morphological characteristics, snapping-resistance, lodging-resistant index, and grain yield. Gaocheng 8901 had higher lodging-resistance but lower grain yield than Yannong 21. Comparing with low planting density (180 x 10(4) basic seedlings per hm2), high planting density (240 x 10(4) basic seedlings per hm2) decreased the culm snapping-resistance and lodging-resistant index of the two varieties, especially Yannong 21.

Ultra-short plasmonic splitters and waveguide cross-over based on coupled surface plasmon slot waveguides.

Composite metal-dielectric-metal (MDM) surface plasmon polariton (SPP) structures are first proposed to realize the ultra-short optical splitters with simplified designs. The operation mechanism is based on the contra-directional coupling achieved in composite plasmonic slot waveguides. In certain cases, the switching function can also be realized.

Flat-plateau supercontinuum generation in liquid absorptive medium by femtosecond filamentation.

We have studied filamentation and supercontinuum generation by focusing the intense femtosecond laser pulses into an absorptive medium (CuSO(4) aqueous solution). A broad spectrum from 350 to 950 nm with a flat plateau spanning approximately from 450 to 700 nm with a flatness of 9% is obtained without any additional filters. The results indicate that the absorptive medium not only suppresses the strong surplus femtosecond laser signal but also flattens the supercontinuum spectrum efficiently.

Fabrication of centimeter-sized single-domain two-dimensional colloidal crystals in a wedge-shaped cell under capillary forces.

Self-assembly of colloidal spheres confined within cells of different shapes formed with two slides under capillary forces are studied. It is found that by controlling the shape of the cell the curvature of the drying front can result in a significant effect on the self-organization process. A curved drying front formed within parallel slides is always associated with growth of colloidal crystal structures with a high density of disorder.

Effects of different water availability at post-anthesis stage on grain nutrition and quality in strong-gluten winter wheat.

Wheat (Triticum aestivum L.) is one of the most important agricultural crops worldwide. However, water is the most important limiting factor for wheat production.

[Correlation of cyclooxygenase 2 with upstream mitogen-activated protein kinase, nuclear factor kappa B signal transduction pathway in middle turbinate mucosa of chronic rhinosinusitis].

Objective: To detect the expression and correlation of cyclooxygenase 2 (COX-2)and key enzymes both of mitogen activated protein kinase (MAPK) and nuclear factor-kappa B( NF-KB) pathways in middle turbinate mucosa of chronic rhinosinusitis (CRS) and to investigate their roles in CRS pathogenesis.

Methods: Twenty-four lateral mucosa of CRS middle turbinates were equally divided into 3 groups according to FESS-97 Haikou criterion (CRS type I stage 2 in group 1, type II stage 2 in group 2, and type III in group 3), and 8 normal mucosa were enrolled as control. Immunohistochemistry and fluorescent real time quantitative polymerase chain reaction (FQ-RT-PCR) were performed to detect the expression of COX-2, ERK, p38MAPK, JNK and NF-kappaB subunits.

[Glucocorticoid receptor subunit expression in adenoid tissue of children with obstructive sleep apnea hypopnea syndrome].

Objective: The expression of glucocorticoid receptor (GR) expression in obstructive sleep apnea hypopnea syndrome (OSAHS) in children is currently unknown. The aim of this study was to determine the GR-alpha and GR-beta status in the adenoidal tissues in children with OSAHS.

Methods: Thirty-four pediatric patients (aged 3-14 years, median 7.

[Diagnosis and treatment of penile verrucous carcinoma: a report of 4 cases].

Objective: To explore the diagnosis and treatment of penile verrucous carcinoma.

Methods: The clinical and pathological data of 4 patients with penile verrucous carcinoma were analyzed.

Results: The patients ranged in age from 42 to 76 years (average 52).