Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
August 2009
Aim: To investigate the expression of chemokine receptor CCR1 in the human colorectal carcinoma and its correlation with metastasis of lymph nodes.
Methods: By immunohistochemistry, the expression of CCR1 was studied in the colorectal carcinoma of 83 cases and 15 normal cases as control subjects.
Results: The positive expression rates of CCR1 in the colorectal carcinoma tissues with deep invasion, poor differentiation, metastasis and higher Dukes' stage were significantly higher than those with superficial invasion (P<0.