Temperature-Dependent Separation of CO from Light Hydrocarbons in a Porous Self-Assembly of Vertexes Sharing Octahedra.

Design of flexible porous materials where the diffusion of guest molecules is regulated by the dynamics of contracted pore aperture is challenging. Here, a flexible porous self-assembly consisting of 1D channels with dynamic bottleneck gates is reported. The dynamic pendant naphthimidazolylmethyl moieties at the channel necks provide kinetic gate function, that enables unusual adsorption for light hydrocarbons.

Fabrication of Lanthanide-Functionalized Hydrogen-Bonded Organic Framework Films for Ratiometric Temperature Sensing by Electrophoretic Deposition.

Developing a noncontact ratiometric luminescent temperature sensor with high sensitivity, widely available emission range, and reliable performance is a challenge in materials science. Herein, we demonstrated that this goal can be achieved by fabricating a lanthanide-functionalized hydrogen-bonded organic framework film (named the Eu@HOF-TCBP film). The unbonded carboxylic groups that existed in the structure not only enable lanthanide ions to bind with the framework for bringing dual emission but also allow for preparing a hydrogen-bonded organic framework (HOF) film through the facile electrophoretic deposition.

Activation and Characterization of Cryptic Gene Cluster: Two Series of Aromatic Polyketides Biosynthesized by Divergent Pathways.

One biosynthetic gene cluster (BGC) usually governs the biosynthesis of a series of compounds exhibiting either the same or similar molecular scaffolds. Reported here is a multiplex activation strategy to awaken a cryptic BGC associated with tetracycline polyketides, resulting in the discovery of compounds having different core structures. By constitutively expressing a positive regulator gene in tandem mode, a single BGC directed the biosynthesis of eight aromatic polyketides with two types of frameworks, two pentacyclic isomers and six glycosylated tetracyclines.

[Expression of protein 4.1 family in melanoma cell lines and its effect on cell proliferation].

Objective: To detect the expression of protein 4.1 family members in mouse melanoma cell lines and evaluate their effect on cell proliferation.

Methods: PCR and Western blot were used to detected to the expression of protein 4.

Leptin attenuates lipopolysaccharide or oleic acid-induced acute lung injury in mice.

Leptin is reported to be involved in acute lung injury (ALI). However, the role and underlying mechanisms of leptin in ALI remain unclear. The aim of this study was to determine whether leptin deficiency promoted the development of ALI.

Electrical impedance scanning in breast tumor imaging: correlation with the growth pattern of lesion.

Background: This study researched the electric impedance properties of breast tissue and demonstrated the different characteristic of electrical impedance scanning (EIS) images.

Methods: The impedance character of 40 malignant tumors, 34 benign tumors and some normal breast tissue from 69 patients undergoing breast surgery was examined by EIS in vivo measurement and mammography screening, with a series of frequencies set between 100 Hz - 100 kHz in the ex vivo spectroscopy measurement.

Results: Of the 39 patients with 40 malignant tumors, 24 showed bright spots, 11 showed dark areas in EIS and 5 showed no specific image.

Molecular cloning of a novel cDNA from Mus muscular BALB/c mice encoding glycosyl hydrolase family 1: a homolog of human lactase-phlorizin hydrolase.

Objective: To study the mechanism of lactose intolerance (LI) by cloning the mouse lactase cDNA and recombining a vector. METHODS Total murine RNA was isolated from the small intestine of a 4-week-old BALB/c mouse (d). Gene-specific primers were designed and synthesized according to the cDNA sequences of lactase-phlorizin hydrolase (LPH) in human, rat, and rabbit.

[A simulation study of electrical impedance scan-imaging based on a phantom].

Objective: To testify the feasibility of electrical impedance scanning (EIS) imaging and to classify the factors influencing EIS imaging at the early stage of electrical impedance scanning breast imaging study.

Method: Based on the EIS experiment workplace, a phantom to simulate the distribution of breast tissue was designed. Using NaCl solution and agar block with different conductance, three kinds of electric fields disturbances were simulated.