Publications by authors named "Zhen-Yang Lin"

Purpose: To predict the efficacy of high-intensity focused ultrasound (HIFU) ablation for uterine leiomyomas based on diffusion tensor imaging (DTI) indicators and imaging features.

Methods: Sixty-two patients with 85 uterine leiomyomas were consecutively enrolled in this retrospective study and underwent DTI scanning before HIFU treatment. Based on whether the non-perfused volume ratio (NPVR) was greater than 70%, all patients were assigned to sufficient ablation (NPVR ≥ 70%) or insufficient ablation (NPVR < 70%) groups.

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Article Synopsis
  • The study investigates how lenalidomide affects human fibroblast-like synovial cells (HFLS) and its therapeutic potential for treating hemophilic arthropathy in a mouse model of hemophilia A.
  • In laboratory tests, lenalidomide was shown to reduce HFLS cell growth and pro-inflammatory cytokine levels, while promoting cell death, especially at lower concentrations.
  • In animal experiments, lenalidomide administration significantly improved joint health by decreasing inflammation and pathological changes compared to untreated mice, indicating its protective effects against hemophilic arthritis.
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Background: Glioma is the most common primary malignant tumor in the central nervous system. Because of the resistance of glioma to chemoradiotherapy and its aggressive growth, the survival rate of patients with glioma has not improved. This study aimed to disclose the effect of retinol dehydrogenase 10 (RDH10) on the migration and invasion of glioma cells, and to explore the potential mechanism.

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A novel asymmetric monosubstituted 1,10-phenanthroline, Hophen.0.5 H(2)O (1, Hophen=1H-[1,10]phenanthrolin-2-one), was generated by a facile route, and a novel class of crystalline, d(10)-metal, monomeric or oligomeric complexes of this ligand, namely [Hg(ophen)(2)].

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