Publications by authors named "Zhen-Yang Liang"
EuroIntervention
July 2013
Article Synopsis
- The study assessed the impact of genetic variations on platelet reactivity in patients with acute coronary syndrome (ACS) after receiving drug-eluting stents (DES) and clopidogrel treatment.
- It involved 1,016 patients and focused on specific genetic markers from CYP3A4/5, CYP2C19, P2Y12, and ABCB1 genes to identify associations with high on-treatment platelet reactivity (HTPR).
- Findings revealed that carrying two CYP2C19 loss-of-function alleles increased the risk of adverse clinical events, such as cardiovascular death and myocardial infarction, without a significant link to bleeding events.
